Results 221 to 230 of about 1,589,246 (309)

Gelatin—Hyaluronic Acid Hydrogels with Tuned Stiffness to Counterbalance Cellular Forces and Promote Cell Differentiation

, 2016
Sara Poveda‐Reyes, Vladimíra Moulisová, Esther Sanmartín‐Masiá, Luis Quintanilla‐Sierra, Manuel Salmerón‐Sánchez, Gloria Gallego Ferrer   +5 more
openalex   +2 more sources

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Promotion of cellular differentiation and DNA repair potential in brain cancer cells by Clitoria ternatea L. with rasayana properties in vitro. [PDF]

J Ayurveda Integr Med
Prasad K, Raghu KS, Maruthiyodan S, Wadhwa R, Kaul SC, Satyamoorthy K, Guruprasad KP.   +6 more
europepmc   +1 more source

MLKL promotes cellular differentiation in myeloid leukemia by facilitating the release of G-CSF. [PDF]

Cell Death Differ, 2021
Wang X, Ros U, Agrawal D, Keller EC, Slotta-Huspenina J, Dill V, Shen B, Shi R, Herold T, Belka C, Mishra R, Bassermann F, Garcia-Saez AJ, Jost PJ.   +13 more
europepmc   +1 more source

Structural and functional characterization of chitinase from carnivorous plant Drosera adelae

FEBS Open Bio, EarlyView.
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda, Yuki Naruse, Yusaku Suizu, Tomohiro Araki, Yoshikazu Hoshi, Haruhiko Sakuraba, Junji Hayashi, Toshihisa Ohshima   +7 more
wiley   +1 more source

Novel Mechanism for an Old Drug: Phenazopyridine is a Kinase Inhibitor Affecting Autophagy and Cellular Differentiation. [PDF]

Front Pharmacol, 2021
Preynat-Seauve O, Nguyen EB, Westermaier Y, Héritier M, Tardy S, Cambet Y, Feyeux M, Caillon A, Scapozza L, Krause KH.   +9 more
europepmc   +1 more source

Supplementary Figures from Epigenome-wide SRC-1–Mediated Gene Silencing Represses Cellular Differentiation in Advanced Breast Cancer

, 2023
Elspeth Ward, Damir Varešlija, Sara Charmsaz, Ailís Fagan, Alacoque L. Browne, Nicola Cosgrove, Sinéad Cocchiglia, Siobhan P. Purcell, Lance Hudson, Sudipto Das, Darran P. O’Connor, Philip J. O’Halloran, Andrew H. Sims, Arnold D. Hill, Leonie S. Young   +14 more
openalex   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source

Epigenetic Clues to Better Understanding of the Asexual Embryogenesis in planta and in vitro

Frontiers in Plant Science, 2019
Taras Pasternak, Denes Dudits
doaj   +1 more source