Results 21 to 30 of about 1,611,391 (358)

Metabolic Control of Cellular Differentiation [PDF]

open access: yesDevelopmental Cell, 2016
The role of metabolic rewiring during cellular differentiation is under intense investigation. Reporting recently in Science, Peng et al. (2016) found that activation of glycolysis supports T helper cell differentiation by controlling acetyl-coA and histone acetylation levels, identifying a link between metabolic state and epigenetic control of gene ...
Vinay, Bulusu, Alexander, Aulehla
openaire   +2 more sources

Mesenchymal stromal cells derived from cervical cancer produce high amounts of adenosine to suppress cytotoxic T lymphocyte functions

open access: yesJournal of Translational Medicine, 2016
Background In recent years, immunomodulatory mechanisms of mesenchymal stem/stromal cells (MSCs) from bone marrow and other “classic” sources have been described. However, the phenotypic and functional properties of tumor MSCs are poorly understood.
María de Lourdes Mora-García   +10 more
doaj   +1 more source

The transcription factor ATF5: role in cellular differentiation, stress responses, and cancer. [PDF]

open access: yes, 2017
Activating transcription factor 5 (ATF5) is a cellular prosurvival transcription factor within the basic leucine zipper (bZip) family that is involved in cellular differentiation and promotes cellular adaptation to stress.
Angelastro, James M, Sears, Thomas K
core   +2 more sources

Heterogeneity and stochastic growth regulation of biliary epithelial cells dictate dynamic epithelial tissue remodeling

open access: yeseLife, 2016
Dynamic remodeling of the intrahepatic biliary epithelial tissue plays key roles in liver regeneration, yet the cellular basis for this process remains unclear.
Kenji Kamimoto   +5 more
doaj   +1 more source

Galectin-12 in Cellular Differentiation, Apoptosis and Polarization. [PDF]

open access: yes, 2018
Galectin-12 is a member of a family of mammalian lectins characterized by their affinity for β-galactosides and consensus amino acid sequences. The protein structure consists of a single polypeptide chain containing two carbohydrate-recognition domains ...
Liu, Fu-Tong, Wan, Lei, Yang, Ri-Yao
core   +2 more sources

Nuclear 2C DNA and genome size analysis in somatic embryo regenerated gladiolus plants using flow cytometry

open access: yesAdvances in Horticultural Science, 2017
Gladiolus is a valuable asexually propagated plant of horticultural importance. Here, in the present communication, in vitro embryogenesis protocol and 2C DNA content of embryo regenerated plant are described.
A. Mujib, M. Ali, D. Tonk, N. Zafar
doaj   +1 more source

Generalized, switch-like competitive heterodimerization networks [PDF]

open access: yes, 2007
High-dimensional switches have been proposed as a way to model cellular differentiation, particularly in the context of basic Helix-Loop-Helix (bHLH) competitive heterodimerization networks.
Cinquin, O, Page, KM
core   +1 more source

CELLULAR DIFFERENTIATION IN THE THYMUS [PDF]

open access: yesThe Journal of Experimental Medicine, 1970
Young adult rat thymus and lymph node cell subpopulations were obtained by differential flotation on discontinuous BSA density gradients and assayed for properties characteristic of mature thymus-derived lymphocytes. One such subpopulation (C) of thymocytes was enriched in its ability to respond mitotically to a hemiallogeneic MLR stimulus, to localize
Daniel G Colley   +2 more
openaire   +1 more source

Phytochemical Composition and Detection of Novel Bioactives in Anther Callus of Catharanthus roseus L.

open access: yesPlants, 2023
Catharanthus roseus L. (G.) Don is the most widely studied plant because of its high pharmacological value. In vitro culture uses various plant parts such as leaves, nodes, internodes and roots for inducing callus and subsequent plant regeneration in C ...
Yashika Bansal   +4 more
doaj   +1 more source

Role of Prion protein-EGFR multimolecular complex during neuronal differentiation of human dental pulp-derived stem cells [PDF]

open access: yes, 2018
Cellular prion protein (PrPC) is expressed in a wide variety of stem cells in which regulates their self-renewal as well as differentiation potential. In this study we investigated the presence of PrPCin human dental pulp-derived stem cells (hDPSCs) and ...
Manganelli, Valeria   +6 more
core   +1 more source

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