Results 71 to 80 of about 4,342,740 (357)

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Phytocompounds and Regulation of Flavonoids in In Vitro-Grown Safflower Plant Tissue by Abiotic Elicitor CdCl₂

Metabolites
In this study, a Gas chromatography–mass spectrometry (GC–MS) investigation of embryogenic callus and somatic embryo regenerated shoots of Carthamus tinctorius revealed the presence of a variety of sugars, sugar acids, sugar alcohols, fatty acids ...
Bushra Ejaz, Abdul Mujib, Rukaya Syeed, Jyoti Mamgain, Moien Qadir Malik, Kanchan Birat, Yaser Hassan Dewir, Katalin Magyar-Tábori   +7 more
doaj   +1 more source

Developmental Disorders in Children Recently Diagnosed With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag, Long Vu, Ritika Miryala, Jeffrey M. Albert, Molly McVoy, Siran M. Koroukian   +5 more
wiley   +1 more source

Dynamic shifts in chromatin states differentially mark the proliferative basal cells and terminally differentiated cells of the developing epidermis

Epigenetics, 2020
Post-translational modifications on nucleosomal histones represent a key epigenetic regulatory mechanism to mediate the complex gene expression, DNA replication, and cell cycle changes that occur in embryonic cells undergoing lineage specification ...
Yan Ting Shue, Kang Ting Lee, Benjamin William Walters, Hui Binn Ong, Shaktheeshwari Silvaraju, Wei Jun Lam, Chin Yan Lim   +6 more
doaj   +1 more source

The Calcium-Sensing Receptor and Integrins in Cellular Differentiation and Migration

Frontiers in Physiology, 2016
The calcium-sensing receptor (CaSR) is a widely expressed homodimeric G-protein coupled receptor structurally related to the metabotropic glutamate receptors and GPRC6A.
S. Tharmalingam, D. Hampson
semanticscholar   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Early Neural Cell Death Is an Extensive, Dynamic Process in the Embryonic Chick and Mouse Retina

The Scientific World Journal, 2013
Orchestrated proliferation, differentiation, and cell death contribute to the generation of the complex cytoarchitecture of the central nervous system, including that of the neuroretina.
Teresa Chavarría, Jimena Baleriola, Raquel Mayordomo, Flora de Pablo, Enrique J. de la Rosa   +4 more
doaj   +1 more source

Cytoprotective and Neurotrophic Effects of Octadecaneuropeptide (ODN) in in vitro and in vivo Models of Neurodegenerative Diseases

Frontiers in Endocrinology, 2020
Octadecaneuropeptide (ODN) and its precursor diazepam-binding inhibitor (DBI) are peptides belonging to the family of endozepines. Endozepines are exclusively produced by astroglial cells in the central nervous system of mammals, and their release is ...
Olfa Masmoudi-Kouki, Amira Namsi, Amira Namsi, Yosra Hamdi, Seyma Bahdoudi, Seyma Bahdoudi, Ikram Ghouili, Julien Chuquet, Jérôme Leprince, Jérôme Leprince, Benjamin Lefranc, Benjamin Lefranc, Taoufik Ghrairi, Marie-Christine Tonon, Gérard Lizard, David Vaudry, David Vaudry   +16 more
doaj   +1 more source

Differences in the Abundance of Auxin Homeostasis Proteins Suggest Their Central Roles for In Vitro Tissue Differentiation in Coffea arabica

Plants, 2021
Coffea arabica is one of the most important crops worldwide. In vitro culture is an alternative for achieving Coffea regeneration, propagation, conservation, genetic improvement, and genome editing.
Ana O. Quintana-Escobar, Hugo A. Méndez-Hernández, Rosa M. Galaz-Ávalos, José M. Elizalde-Contreras, Francisco A. Reyes-Soria, Victor Aguilar-Hernández, Eliel Ruíz-May, Víctor M. Loyola-Vargas   +7 more
doaj   +1 more source

Slowdown of growth controls cellular differentiation

Molecular Systems Biology, 2016
How can changes in growth rate affect the regulatory networks behavior and the outcomes of cellular differentiation? We address this question by focusing on starvation response in sporulating Bacillus subtilis.
J. Narula, A. Kuchina, Fang Zhang, M. Fujita, Gürol M. Süel, O. Igoshin   +5 more
semanticscholar   +1 more source