Results 121 to 130 of about 82,213 (306)

Direct Numerical Simulations of Oxygen-flame-driven Deflagration-to-detonation Transition in Type Ia Supernovae

The Astrophysical Journal
We present direct numerical simulations demonstrating deflagration-to-detonation transition (DDT) driven by oxygen flames in Type Ia supernova progenitors.
Xiaoyu Zhang, Lile Wang, Yang Gao, Yao Zhou   +3 more
doaj   +1 more source

AI‐Driven Acceleration of Fluorescence Probe Discovery

Advanced Science, EarlyView.
We present PROBY, an AI model trained on large‐scale datasets to predict key photophysical properties and accelerate the discovery of target‐specific fluorescent probes. By screening a target‐annotated library, PROBY identifies candidate probes for diverse targets and could guide probe optimization, enabling a range of in vitro and in vivo imaging ...
Xuefeng Jiang, Yanbo Li, Xue Tian, Sen Yang, Ruina Luo, Cenxing Zhou, Yuxuan Liu, Jingying Hu, Sen Feng, Lu Gan, Chongzhao Ran, Kun‐Hsing Yu, Junhan Zhao, Xiao Han, Xuan Zhai, Yuntao Jia, Jiapei Dai, Xiyue Wang, Biyue Zhu   +18 more
wiley   +1 more source

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

Islet Amyloid Polypeptide Modelled to Simulate Diabetes Co‐Oligomerized with β‐Amyloid 1‐42 Reproducing the Pathological Cascade of Alzheimer's Disease in Human Cerebral Organoids

Advanced Science, EarlyView.
Human islet amyloid polypeptide (hIAPP) was used to mimic T2DM, and Aβ42‐hIAPP co‐oligomers were delivered into the human mature cerebral organoids (COs), which reproduce typical AD pathology and significant neuronal death more closely resembling that of AD patients.
Jin Yan, Zhimeng Tang, Yanyu Luo, Bin Liu, Xinxin Huang, Jun Wei, Feng Yue   +6 more
wiley   +1 more source

Numerical Structure Analysis of Regular Hydrogen-Oxygen Detonations [PDF]

, 2003
Large-scale numerical simulations have been carried out to analyze the internal wave structure of a regular oscillating low-pressure H2 : O2 : Ar-Chapman-Jouguet detonation in two and three space-dimensions.
Deiterding, Ralf
core  

Superelastic High‐Entropy Oxide Ceramic Aerogels for Thermal Superinsulation and Sealing at Extreme Conditions

Advanced Science, EarlyView.
A high‐entropy oxide ceramic of (Gd1/2Lu1/2)2(Ti1/3Zr1/3Hf1/3)2O7 is prepared through a molecular synthesis route of pyrolytic solid‐solution reactions. The architectured nanofiber aerogel manifests unprecedented thermomechanical properties, including superelastic compressibility of 98% from −196 to 1500 °C, and thermal superinsulation capacity (24.14 ...
Xiaoke Jiang, Tao Du, Hengzhong Fan, Junhong Liu, Yunfeng Su, Peng He, Hongxiang Chen, Litian Hu, Yongsheng Zhang, Qiangqiang Zhang   +9 more
wiley   +1 more source

Exposure to BDE-209 triggers necroptosis by activating the JAK2/STAT3 signaling pathway, thereby exacerbating neuroinflammation

Ecotoxicology and Environmental Safety
Polybrominated diphenyl ethers (PBDEs), a class of brominated flame retardants, are extensively employed in industrial applications. Among these, decabromodiphenyl ether (BDE-209), the predominant congener, is widely incorporated into consumer materials ...
Jing Yang, Liujiangshan Jiang, Haonan Ma, Yapei Zhu, Xuan Zhao, Tianyao Yang, Wei Liu   +6 more
doaj   +1 more source

Membrane‐Mediated Force Transduction Drives Stick‐Slip Motion of Lipid Vesicles

Advanced Science, EarlyView.
A rotating magnetic field actuates a ferromagnetic particle inside a lipid vesicle, generating internal flows that induce stick‐slip propulsion near a surface. Membrane properties—elasticity, excess area, and phase behavior—modulate this motion by shaping stress dissipation and force transduction.
Paula Magrinya, Arin Escobar Ortiz, Juan L. Aragones, Laura R. Arriaga   +3 more
wiley   +1 more source

Hierarchical Strain‐Modified Medium‐Entropy Carbide Ceramics Exhibit Exceptional Ablation Resistance up to 2400°C

Advanced Science, EarlyView.
A novel strategy is developed by doping reduced graphene oxide (rGO) into a (HfZrTi)C medium‐entropy ceramic. This induces a hierarchical strain modification mechanism, synergistically inhibiting crack propagation at the microscale and dissipating stress at the mesoscale.
Junyi Xiao, Pengfei He, Lin Xue, Shujun Hu, Liliang Shao, Chuan Sun, Yunyun Ge, Jiangbo Cheng, Xiubing Liang   +8 more
wiley   +1 more source

Flame-retardant sustainable sandwich beams with 3D-Printed peanut-shaped cellular cores and natural composite face sheets: Structural analysis

Case Studies in Thermal Engineering
This study investigates the structural behavior of a novel type of eco-friendly sandwich beam, combining 3D-printed peanut-shaped cellular cores and natural composite face sheets, taking flammability considerations into account.
Saeed Kamarian, Hamidreza Goodarzi, Ehsan Heidarizadi, Reza Barbaz-Isfahani, Maksym Li, Saeed Saber-Samandari, Jung-il Song   +6 more
doaj   +1 more source