Results 81 to 90 of about 870,597 (289)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Advanced solar concentrator mass production, operation, and maintenance cost assessment [PDF]

open access: yes
The object of this assessment was to estimate the costs of the preliminary design at: production rates of 100 to 1,000,000 concentrators per year; concentrators per aperture diameters of 5, 10, 11, and 15 meters; and various receiver/power conversion ...
Bedard, R. J.   +2 more
core   +1 more source

Human Amniocytes Are Receptive to Chemically Induced Reprogramming to Pluripotency [PDF]

open access: yes, 2017
Restoring pluripotency using chemical compounds alone would be a major step forward in developing clinical-grade pluripotent stem cells, but this has not yet been reported in human cells.
Adjaye, J   +15 more
core   +4 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Chronic cranial window with access port for repeated cellular manipulations, drug application, and electrophysiology

open access: yesFrontiers in Cellular Neuroscience, 2014
Chronic cranial windows have been instrumental in advancing optical studies in vivo, permitting long-term, high-resolution imaging in various brain regions. However, once a window is attached it is difficult to regain access to the brain under the window
Christopher Joel Roome, Bernd eKuhn
doaj   +1 more source

Bio-Foaming Agent Used for Preparing Cellular Glass from Recycled Residual Glass

open access: yes, 2023
Cellular glass from powders of recycled residual glass, borax as a fluxing agent, and elm leaves as a bio-foaming agent thermally treated at over 825ºC by unconventional microwave heating (according to the own technique) was experimentally manufactured.
LUCIAN, PĂUNESCU   +4 more
openaire   +1 more source

Parabolic Dish Concentrator (PDC-2) Development [PDF]

open access: yes, 1984
The design of the Parabolic Dish Concentrator (PDC-2) is described. The following five subsystems of the concentrator are discussed: (1) reflective surface subsystem, (2) support structure subsystem, (3) foundation, (4) drive subsystem, and (5 ...
Rafinejad, D.
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

EXPANDING RESIDUAL CLEAR FLAT GLASS WITH COAL POWDER IN OXIDANT ATMOSPHERE OF THE OVEN USING WATER GLASS SOLUTION

open access: yesNonconventional Technologies Review, 2023
Porous material based on residual glass was non-conventionally made using anthracite as a pore-forming agent under the conditions of an oven with oxidizing atmosphere. Water glass as a protective agent for carbon particles avoiding their early oxidation
Lucian Paunescu   +2 more
doaj  

5G Cellular User Equipment: From Theory to Practical Hardware Design

open access: yes, 2017
Research and development on the next generation wireless systems, namely 5G, has experienced explosive growth in recent years. In the physical layer (PHY), the massive multiple-input-multiple-output (MIMO) technique and the use of high GHz frequency ...
Dong, Xiaodai, Huo, Yiming, Xu, Wei
core   +1 more source

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