Results 151 to 160 of about 2,153,248 (300)

Pneumococcus uses COMMD2 to alter host cellular immunity. [PDF]

Nat Commun
Connor MG, Sanchez L, Chevalier C, Camarasa TMN, Carvalho F, Eldridge MJG, Chaze T, Matondo M, Karkeni E, Dufour S, Impens F, Baumgarten S, Enninga J, Hamon MA.   +13 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Influence of SARS-CoV-2 mRNA BNT161b2 Vaccination on Humoral and Cellular Immunity in Pediatric Stem Cell Transplant Patients

INFLUENCE OF SARS-COV-2 MRNA BNT161B2 VACCINATION ON HUMORAL AND CELLULAR IMMUNITY IN PEDIATRIC STEM CELL TRANSPLANT PATIENTS Influence of SARS-CoV-2 mRNA BNT161b2 Vaccination on Humoral and Cellular Immunity in Pediatric Stem Cell Transplant Patients /
Thole, Linda Marie Laura
core  

Subversion of Atypical Mucin Traps by a Spore-Coat Effector Blocks Cellular Immunity in Drosophila. [PDF]

Adv Sci (Weinh)
Li S, Chen H, Fang G, Wei D, Wu H, Chen C, Hong S, Wang C.   +7 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Our archaic heritage: the innate immunity. The cellular immunity of Drosophila [Ösi örökségünk: a veleszületett immunitás. A Drosophila sejtes immunitása]

, 2003
Authors describe the essentials of the cellular immunity of Drosophila. They describe the Drosophila CD system, the main blood cell lineages and a blood cell differentiation model based on the expression of the CD antigens.
Hultmark, Dan,, Róbert, Márkus, Gateff, Elisabeth, Balázs, Váczi, László, Fehér, Rus, Florentina, Lános, Zsámboki, Kurucz, Éva, Barbara, Laurinyecz, István, Nagy, István, Andó   +10 more
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

A <i>Ganoderma lucidum</i> Polysaccharide-Modified Nanoadjuvant Elicits Potent Cellular Immunity for Hepatitis B Vaccine. [PDF]

Vaccines (Basel)
Zhai Z, You J, Liu X.
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Manganese Pyrophosphate Mineralized DNA Nanovaccine Elicits Potent Humoral and Cellular Immunity. [PDF]

Angew Chem Int Ed Engl
Dang S, Sun Y, Chen L, Dong Y, Han Z, Hou J, Wang X, Kang Z, Liu Z, Wang Z, Li Q, Ren J, Li F.   +12 more
europepmc   +1 more source