Results 281 to 290 of about 3,445,878 (379)

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Pathogenesis of early phase experimental allergic neuritis: DAILY MONITORING OF HUMORAL AND CELLULAR IMMUNE RESPONSE TO PERIPHERAL NERVE ANTIGEN

, 1979
G.K. Molnár, Matti K. Viljanen, Paavo Riekkinen   +2 more
openalex   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Cellular Immunity to Encephalitogenic Factor as Measured by Macrophage Migration Inhibition During Tumour Induction and Growth

, 1978
David J. Flavell, J R Goepel, C. W. Potter, Ian Carr   +3 more
openalex   +2 more sources

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Differential cellular immune responsiveness to systems of the major histocompatibility complex

, 1976
Fritz H. Bach
openalex   +1 more source

Tetraspanin CD37 contributes to the initiation of cellular immunity by promoting dendritic cell migration

European Journal of Immunology, 2013
Kate H. Gartlan, J. Wee, M. Demaria, R. Nastovska, T. M. Chang, E. Jones, V. Apostolopoulos, G. Pietersz, M. Hickey, A. Spriel, M. Wright   +10 more
semanticscholar   +1 more source

Immunodeficiency Diseases and Tumor Immunobiology [PDF]

, 1974
Abramoff, Peter A., Duquesnoy, Rene J.
core   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source

Parasitoid wasp venom SERCA regulates Drosophila calcium levels and inhibits cellular immunity

Proceedings of the National Academy of Sciences of the United States of America, 2013
Nathan T. Mortimer, Jeremy Goecks, B. Kacsoh, J. Mobley, Gregory J. Bowersock, James Taylor, T. Schlenke   +6 more
semanticscholar   +1 more source