Results 311 to 320 of about 3,445,878 (379)

ADAPT NXT: Fixed Cycles or Every‐Other‐Week IV Efgartigimod in Generalized Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This phase 3b, open‐label, randomized ADAPT NXT study investigated the efficacy, safety, and tolerability of efgartigimod administered in either a fixed cycles dosing regimen (3 cycles of 4 once‐weekly infusions, with 4 weeks between cycles) or a cycle followed by every‐other‐week (Q2W) dosing.
Ali A. Habib, Kristl G. Claeys, Vera Bril, Yessar Hussain, Kelly Gwathmey, Gregory Sahagian, Elena Cortés‐Vicente, Edward Brauer, Deborah Gelinas, Anne Sumbul, Rosa H. Jimenez, Daniela Hristova, Delphine Masschaele, Renato Mantegazza, Andreas Meisel, Shahram Attarian, On behalf of the ADAPT NXT Study Group   +16 more
wiley   +1 more source

CNS Mitochondria‐Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial dysfunction is a hallmark of neurodegenerative diseases like Alzheimer's (AD) and Parkinson's (PD). Our goal was to develop practical, noninvasive methods to assess mitochondrial status through the detection of mitochondria‐derived vesicles (MDVs).
Qi Liu, Wentao Chen, Yahong Wu, Zhen Guo, Jun Chen, Chen Tian, Pan Wang, Shaopeng Zeng, Bin Xu, Jing Duan, Shilong Han, Xiao Xiong, Jing Zhang   +12 more
wiley   +1 more source

Discontinuation of Immunotherapy in Patients With Relapsing Myelitis Without AQP4/MOG Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study assesses the outcomes of immunotherapy discontinuation in patients with relapsing seronegative idiopathic myelitis (SIM), a condition that remains uninvestigated due to its rarity. We reviewed records from 77 patients with relapsing SIM at the National Cancer Center of Korea, focusing on 11 who discontinued treatment after a median ...
Ki Hoon Kim, You‐Ri Kang, Jae‐Won Hyun, Su‐Hyun Kim, Ho Jin Kim   +4 more
wiley   +1 more source

A PANoptosis‐Based Signature for Survival and Immune Predication in Glioblastoma Multiforme

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PANoptosis is a concept of total cell death characterized by pyroptosis, apoptosis, and necroptosis. We aimed to explore the clinical significance of PANoptosis‐related genes (PARGs) in glioblastoma multiforme (GBM). Methods Expression profiles of GBM were downloaded from the XENA database as a training dataset to construct a ...
Jun Yang, Da Lin, Dongyuan Liu, Dongxu Zhang, Hao Wang   +4 more
wiley   +1 more source

[Fertility reduction by cellular immune reaction against spermatozoa antigens].

, 1979
Liselotte Mettler, H. R. Tinneberg, Robert Birke, K. Semm   +3 more
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Cellular immunity to nephroblastoma

International Journal of Cancer, 1971
AbstractLymphocytes from 24 patients with nephroblastoma and 24 controls have been tested for tumor‐related cytotoxicity in vitro. The micro‐plate technique has been applied in 26 tests and the cytotoxic plaque test in eight.In 10 out of 24 nephroblastoma patients with two autochthonous and eight allogeneic combinations, tumor‐related cell‐mediated ...
Berta Jereb, Volker Diehl, Carol O'toole, L. Åhström, J. Stjernswärd   +4 more
openaire   +3 more sources

Cellular Antimicrobial Immunity

CRC Critical Reviews in Microbiology, 1979
Acquired resistance to infectious disease may be expressed by a predominantly humoral or a cellular mechanism or, more frequently, by a combination of the two. The cellular interactions which are responsible for the induction of the immune response in the skin, lung, intestinal mucosa, genitourinary tract, conjunctiva, and peritoneal cavity are ...
Frank M. Collins, Nancy N. Pearsall
openaire   +3 more sources

Hyperthermia and Cellular Immunity

JAMA: The Journal of the American Medical Association, 1976
To the Editor.— In addition to conventional therapeusis employed for the treatment of cancer (eg, chemotherapy, radiation therapy, and surgery), the use of hyperthermia and hypothermia as a means of selectively destroying malignant cells received increased attention in the 1960s.
Patrick D. Guinan, Rashid A. Bhatti, Richard J. Ablin   +2 more
openaire   +2 more sources

Cellular Immune Suppression

2018
chap.
Chi, D.S., Quéré, Pascale, Thorbecke, G.J.   +2 more
openaire   +4 more sources

Nutrition and cellular immunity

International Journal of Immunopharmacology, 1992
We have investigated the influence of nutrition on immune function in animals and man over the past two decades. The profound impairment of immune function that had not been observed in children in developing countries could not consistently be reproduced in the laboratory setting; paradoxically, moderate nutritional restriction could even enhance T ...
Robert A. Good, Ellen Lorenz
openaire   +3 more sources