Results 101 to 110 of about 1,492,586 (335)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Analysis of Statistical QoS in Half Duplex and Full Duplex Dense Heterogeneous Cellular Networks [PDF]
, 2017 Statistical QoS provisioning as an important performance metric in analyzing next generation mobile cellular network, aka 5G, is investigated. In this context, by quantifying the performance in terms of the effective capacity, we introduce a lower bound ...
Lahouti, Farshad +3 more
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Journal of Telecommunications and Information Technology, 2018 There are many scenarios that have been proposed for fifth generation (5G) networks. Some of them, if implemented, will bring fundamental changes at the architectural and node level.
Toha Ardi Nugraha +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
InterCarto. InterGIS, 2015 For the first time based on the developed technique the authors studied the spatial structure of consumption of the Internet traffic in the MTS network in the territory of a large city - Krasnodar.
A. V. Pogorelov +2 more
doaj +1 more source
Identification of Optimal Drug Combinations Targeting Cellular Networks: Integrating Phospho-Proteomics and Computational Network Analysis [PDF]
, 2010 Sergio Iadevaia +4 more
openalex +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Probability bounds of cross‐layer interference in femtocell‐underlay cellular networks employing interference alignment [PDF]
, 2019 Alireza Ghiamatyoun, Ali Olfat
openalex +1 more source