Results 91 to 100 of about 6,348,214 (302)

Mask protein keeps NF-κB precursor inactive by inducing a closed conformation and isolating it in biomolecular condensates

Cell Reports
Summary: Nuclear factor κB (NF-κB) family transcription factors are critical for innate immune responses across a variety of organisms and are frequently dysregulated in diseases.
Kewei Zheng, Xiawei Huang, Xiaojiang Yang, Jiahui Wang, Minhuang Hu, Chengfang Wu, Bo Liu   +6 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

A Cellular Neural Network with Time Sequential Input [PDF]

, 1998
A cellular neura1 network with nesequentia1 input is investigated. In our model, Hebb rule is used as an unsupervised learning ru1e. With respect to learning rate C and slope of sigmoid functionε, four phases are observed,i. e.,ordering state. disordered
工藤, 清, 鈴木, 英俊, 小穴, 真裕, 山下, 修, 森, 崇, 中村, 量空, 上杉, 忠孝, 小田桐, 良一   +7 more
core  

Approximate inter-cell interference modeling for cellular network

, 2011
In this paper, we develop and analyze several inter-cell interference modeling methods for cellular network. The models can analyze multiple interfering signals under different fading scenarios. Incoherent addition of summing multiple interfering signals
Xiang, Wei, Wang, Yafeng, Wei, Guoxing
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Interference Management using Power Control for Device-to-Device Communication in Future Cellular Network

Journal of Telecommunications and Information Technology, 2018
There are many scenarios that have been proposed for fifth generation (5G) networks. Some of them, if implemented, will bring fundamental changes at the architectural and node level.
Toha Ardi Nugraha, Muhammad Putra Pamungkas, Anna Nur Nazilah Chamim   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

SPATIAL STRUCTURE OF INTERNET-TRAFIC CONSUMPTION IN THE MTS NETWORK IN A LARGE CITY (BASED ON KRASNODAR DATA)

InterCarto. InterGIS, 2015
For the first time based on the developed technique the authors studied the spatial structure of consumption of the Internet traffic in the MTS network in the territory of a large city - Krasnodar.
A. V. Pogorelov, K. R. Golovan, M. V. Kuzyakina   +2 more
doaj   +1 more source