Results 1 to 10 of about 21,526 (148)
Tolerogenic dendritic cells in radiation-induced lung injury [PDF]
Frontiers in Immunology, 2023 Radiation-induced lung injury is a common complication associated with radiotherapy. It is characterized by early-stage radiation pneumonia and subsequent radiation pulmonary fibrosis.
Benbo Liu +3 more
doaj +4 more sources
Regulatory multitasking of tolerogenic dendritic cells – lessons taken from Vitamin D3-treated tolerogenic dendritic cells [PDF]
Frontiers in Immunology, 2013 Tolerogenic dendritic cells (DCs) work through silencing of differentiated antigen-specific T cells, activation and expansion of naturally occurring T regulatory cells (Tregs), transfer of regulatory properties to T cells and the differentiation of na ...
Tatjana eNikolic, Bart eRoep
doaj +5 more sources
Metabolism Is Central to Tolerogenic Dendritic Cell Function [PDF]
Mediators of Inflammation, 2016 Immunological tolerance is a fundamental tenant of immune homeostasis and overall health. Self-tolerance is a critical component of the immune system that allows for the recognition of self, resulting in hyporeactivity instead of immunogenicity ...
Wen Jing Sim +2 more
doaj +4 more sources
Life and death of tolerogenic dendritic cells. [PDF]
Trends Immunol, 2023 In contrast to conventional dendritic cells (cDCs) that are constantly exposed to microbial signals at anatomical barriers, cDCs in systemic lymphoid organs are sheltered from proinflammatory stimulation in the steady state but respond to inflammatory signals by gaining specific immune functions in a process referred to as maturation.
Bourque J, Hawiger D.
europepmc +3 more sources
Identification of prognostic genes associated with tolerogenic dendritic cells in gastric cancer based on transcriptomic data. [PDF]
PLoS ONEBackgroundTolerogenic dendritic cells have a pivotal function in treating autoimmune illnesses, atopic diseases, and neoplasms. The precise mechanism by which Tolerogenic dendritic cells function in gastric cancer remains incompletely understood ...
Shenyu Luo +7 more
doaj +2 more sources
Induction of Tolerogenic Dendritic Cells by a Noncoding Oligonucleotide. [PDF]
Eur J ImmunolABSTRACT Tolerogenic dendritic cells (tolDCs) that dampen T cell responses can be induced from blood monocytes in vitro using factors such as Vitamin D3 (VitD), dexamethasone, IL‐10, or rapamycin. However, challenges remain in obtaining robust and efficient generation of cell therapy‐based tolDCs without ...
Kamal K +4 more
europepmc +3 more sources
Ethyl Pyruvate Induces Tolerogenic Dendritic Cells [PDF]
Frontiers in Immunology, 2019 Dendritic cells (DC) are professional antigen presenting cells that have a key role in shaping the immune response. Tolerogenic DC (tolDC) have immuno-regulatory properties and they are a promising prospective therapy for multiple sclerosis and other ...
Neda Djedovic +9 more
doaj +8 more sources
Tolerogenic dendritic cells in organ transplantation. [PDF]
Transpl Int, 2020 Dendritic cells (DCs) are specialized cells of the innate immune system that are characterized by their ability to take up, process and present antigens (Ag) to effector T cells. They are derived from DC precursors produced in the bone marrow. Different DC subsets have been described according to lineage-specific transcription factors required for ...
Ochando J +4 more
europepmc +4 more sources
Natural and Induced Tolerogenic Dendritic Cells. [PDF]
J Immunol, 2020 Abstract Dendritic cells (DCs) are highly susceptible to extrinsic signals that modify the functions of these crucial APCs. Maturation of DCs induced by diverse proinflammatory conditions promotes immune responses, but certain signals also induce tolerogenic functions in DCs.
Iberg CA, Hawiger D.
europepmc +4 more sources
Tolerogenic dendritic cells and their applications in transplantation [PDF]
Cellular and Molecular Immunology, 2014 In transplantation immunology, the ultimate goal is always to successfully and specifically induce immune tolerance of allografts. Tolerogenic dendritic cells (tol-DCs) with immunoregulatory functions have attracted much attention as they play important roles in inducing and maintaining immune tolerance.
Bingyi Shi, Li Haibin
exaly +3 more sources