Tolerogenic dendritic cells in radiation-induced lung injury [PDF]
Frontiers in Immunology, 2023 Radiation-induced lung injury is a common complication associated with radiotherapy. It is characterized by early-stage radiation pneumonia and subsequent radiation pulmonary fibrosis.
Benbo Liu +3 more
doaj +2 more sources
Identification of prognostic genes associated with tolerogenic dendritic cells in gastric cancer based on transcriptomic data. [PDF]
PLoS ONEBackgroundTolerogenic dendritic cells have a pivotal function in treating autoimmune illnesses, atopic diseases, and neoplasms. The precise mechanism by which Tolerogenic dendritic cells function in gastric cancer remains incompletely understood ...
Shenyu Luo +7 more
doaj +2 more sources
Distinct metabolic states guide maturation of inflammatory and tolerogenic dendritic cells [PDF]
Nature Communications, 2022 Assessing metabolic activity within single cells rather than at a population level has a number of advantages. Here, the authors use a flow and mass cytometry based approach that assess the metabolic differences between populations of human immune ...
Juraj Adamik +8 more
doaj +2 more sources
Porphyromonas gingivalis outer membrane vesicles prevent the induction of tolerogenic dendritic cells by first trimester trophoblast cells [PDF]
Frontiers in ImmunologyIntroductionPeriodontitis is a risk factor for adverse pregnancy outcomes, yet the mechanisms linking Porphyromonas gingivalis (Pg) to placental immune dysregulation remain unclear. Outer membrane vesicles (OMV) derived from this pathogen act as systemic
Brenda Lara +10 more
doaj +2 more sources
The Evaluation of the Effect of Tolerogenic Probiotics on the Maturation of Healthy Dendritic Cells versus Immature Dendritic Cells [PDF]
Iranian Journal of Immunology, 2023 Background: Dendritic cells, (DCs) as one of the important immune cell populations, are responsible for the initiation, development, and control of acquired immune responses.
Maryam Rastin +5 more
doaj +1 more source
Involvement of suppressive B-lymphocytes in the mechanism of tolerogenic dendritic cell reversal of type 1 diabetes in NOD mice. [PDF]
PLoS ONE, 2014 The objective of the study was to identify immune cell populations, in addition to Foxp3+ T-regulatory cells, that participate in the mechanisms of action of tolerogenic dendritic cells shown to prevent and reverse type 1 diabetes in the Non-Obese ...
Valentina Di Caro +5 more
doaj +1 more source
Tolerogenic dendritic cell reporting: Has a minimum information model made a difference? [PDF]
PeerJ, 2023 Minimum information models are reporting frameworks that describe the essential information that needs to be provided in a publication, so that the work can be repeated or compared to other work.
Ayesha Sahar +5 more
doaj +2 more sources
Protocol of generation of tolerogenic dendritic cells affects their transcriptional and metabolic profiles leading to specific tolerogenic functions. [PDF]
Mol Ther Methods Clin DevSuuring M +13 more
europepmc +2 more sources
Differential gene expression in thrombomodulin (TM; CD141)(+) and TM(-) dendritic cell subsets. [PDF]
PLoS ONE, 2013 Previously we have shown in a mouse model of bronchial asthma that thrombomodulin can convert immunogenic conventional dendritic cells into tolerogenic dendritic cells while inducing its own expression on their cell surface.
Masaaki Toda +9 more
doaj +1 more source
The role of dendritic cells and their immunometabolism in rheumatoid arthritis
Frontiers in Immunology, 2023 Dendritic cells (DCs) play crucial roles in the pathogenesis of rheumatoid arthritis (RA), a prototypic autoimmune disease characterized by chronic synovitis and joint destruction.
Yuichi Suwa +4 more
doaj +1 more source