Interferon-α abrogates tolerance induction by human tolerogenic dendritic cells. [PDF]
PLoS ONE, 2011 BACKGROUND: Administration of interferon-α (IFN-α) represents an approved adjuvant therapy as reported for malignancies like melanoma and several viral infections.
Nicole Bacher +4 more
doaj +2 more sources
Frontiers in Immunology, 2012 The use of immunosuppressive drugs to treat transplant recipients has markedly reduced the incidence of acute rejection and early graft loss. However, such treatments have numerous adverse side effects and fail to prevent chronic allograft dysfunction ...
Aurelie eMoreau +6 more
doaj +3 more sources
Induction of Tolerogenic Dendritic Cells by Endogenous Biomolecules: An Update [PDF]
Frontiers in Immunology, 2018 The importance of microenvironment on dendritic cell (DC) function and development has been strongly established during the last two decades. Although DCs with general tolerogenic characteristics have been isolated and defined as a particular sub ...
Urban Švajger +2 more
doaj +2 more sources
Humoral immune response to adenovirus induce tolerogenic bystander dendritic cells that promote generation of regulatory T cells. [PDF]
PLoS Pathogens, 2018 Following repeated encounters with adenoviruses most of us develop robust humoral and cellular immune responses that are thought to act together to combat ongoing and subsequent infections.
Thi Thu Phuong Tran +7 more
doaj +2 more sources
Regulatory Macrophages and Tolerogenic Dendritic Cells in Myeloid Regulatory Cell-Based Therapies. [PDF]
Int J Mol Sci, 2021 Suuring M, Moreau A.
europepmc +2 more sources
The Evaluation of the Effect of Tolerogenic Probiotics on the Maturation of Healthy Dendritic Cells versus Immature Dendritic Cells [PDF]
Iranian Journal of Immunology, 2023 Background: Dendritic cells, (DCs) as one of the important immune cell populations, are responsible for the initiation, development, and control of acquired immune responses.
Maryam Rastin +5 more
doaj +1 more source
Tolerogenic dendritic cells [PDF]
Seminars in Immunopathology, 2016 Deficits in immunological tolerance against self-antigens and antigens provided by the diet and commensal microbiota can result in the development of inflammatory and autoimmune disorders. Dendritic cells (DCs) are pivotal regulators of the immune response, specialized in antigen presentation to drive T cell priming and differentiation. DCs also have a
Maisa C. Takenaka, Francisco J. Quintana
openaire +2 more sources
Tolerogenicity is not an absolute property of a dendritic cell [PDF]
European Journal of Immunology, 2010 AbstractPharmacological modulation is known to temper the immune capacity of DC, enhancing the notion that modulated Ag‐bearing DC might be used therapeutically to induce tolerance. We have investigated phenotypic features shared by such DC, and queried their potential to tolerize in different settings. Immature, IL‐10, TGF‐β and 1α,25‐dihydroxyvitamin
Farquhar, Claire A. +9 more
openaire +3 more sources
Tolerogenic Dendritic Cell-Based Approaches in Autoimmunity [PDF]
International Journal of Molecular Sciences, 2021 Dendritic cells (DCs) dictate the outcomes of tissue-specific immune responses. In the context of autoimmune diseases, DCs instruct T cells to respond to antigens (Ags), including self-Ags, leading to organ damage, or to becoming regulatory T cells (Tregs) promoting and perpetuating immune tolerance.
Passeri, Laura +3 more
openaire +2 more sources
Tolerogenic dendritic cell reporting: Has a minimum information model made a difference? [PDF]
PeerJ, 2023 Minimum information models are reporting frameworks that describe the essential information that needs to be provided in a publication, so that the work can be repeated or compared to other work.
Ayesha Sahar +5 more
doaj +2 more sources