Results 11 to 20 of about 4,498,564 (240)
Regulatory multitasking of tolerogenic dendritic cells – lessons taken from Vitamin D3-treated tolerogenic dendritic cells [PDF]
Frontiers in Immunology, 2013 Tolerogenic dendritic cells (DCs) work through silencing of differentiated antigen-specific T cells, activation and expansion of naturally occurring T regulatory cells (Tregs), transfer of regulatory properties to T cells and the differentiation of na ...
Tatjana eNikolic, Bart eRoep
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Metabolism Is Central to Tolerogenic Dendritic Cell Function [PDF]
Mediators of Inflammation, 2016 Immunological tolerance is a fundamental tenant of immune homeostasis and overall health. Self-tolerance is a critical component of the immune system that allows for the recognition of self, resulting in hyporeactivity instead of immunogenicity ...
Wen Jing Sim +2 more
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Understand tolerogenic dendritic cells.
Blood, 2007 In this issue of Blood, Bros and colleagues report thoroughly how glucocorticoid (GC) treatment of a murine dendritic cell (DC) line during maturation induces a stable dendritic cell state with tolerogenic characteristics, similar to that described with ...
Nößner, E., Tschoep, K.E.
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Ethyl Pyruvate Induces Tolerogenic Dendritic Cells [PDF]
Frontiers in Immunology, 2019 Dendritic cells (DC) are professional antigen presenting cells that have a key role in shaping the immune response. Tolerogenic DC (tolDC) have immuno-regulatory properties and they are a promising prospective therapy for multiple sclerosis and other ...
Neda Djedovic +9 more
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Tolerogenic dendritic cell therapy in organ transplantation [PDF]
Transplant International, 2016 International audienceAlthough the occurrence of acute rejection was significantly reduced and the allograft survival at 1 year was massively improved by the development of pharmacological immunosuppressive drugs, little progress has been made regarding ...
Alliot-Licht, Brigitte +7 more
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TOLEROGENIC AND ACTIVATORY PLASMACYTOID DENDRITIC CELLS IN AUTOIMMUNITY [PDF]
Frontiers in Immunology, 2013 Plasmacytoid dendritic cells (pDCs) are a particular subset of DCs that link innate and adaptive immunity. They are responsible for the substantial production of type 1 interferon (IFN-I) in response to viral RNA or DNA through activation of TLR7 and 9 ...
Leslie eGuery, Stephanie eHugues
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Tolerogenic dendritic cells for regulatory T cell induction in man [PDF]
Frontiers in Immunology, 2015 Dendritic cells are (DC) highly specialized professional antigen-presenting cells (APC) that regulate immune responses, maintaining the balance between tolerance and immunity. Mechanisms via which they can promote central and peripheral tolerance include
Verena eRaker +2 more
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Dendritic cell regulation of immunity to Leishmania donovani [PDF]
, 2010 Dendritic cells lie at the interface of innate and adaptive immunity, critically contributing to the generation of an antigen-specific immune response.
Owens, Benjamin M.J.
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Life and death of tolerogenic dendritic cells. [PDF]
Trends Immunol, 2023 In contrast to conventional dendritic cells (cDCs) that are constantly exposed to microbial signals at anatomical barriers, cDCs in systemic lymphoid organs are sheltered from proinflammatory stimulation in the steady state but respond to inflammatory signals by gaining specific immune functions in a process referred to as maturation.
Bourque J, Hawiger D.
europepmc +3 more sources
Natural and Induced Tolerogenic Dendritic Cells [PDF]
The Journal of Immunology, 2020 Abstract Dendritic cells (DCs) are highly susceptible to extrinsic signals that modify the functions of these crucial APCs. Maturation of DCs induced by diverse proinflammatory conditions promotes immune responses, but certain signals also induce tolerogenic functions in DCs.
Courtney A, Iberg, Daniel, Hawiger
openaire +2 more sources