Results 31 to 40 of about 24,183 (235)

Differential gene expression in thrombomodulin (TM; CD141)(+) and TM(-) dendritic cell subsets. [PDF]

PLoS ONE, 2013
Previously we have shown in a mouse model of bronchial asthma that thrombomodulin can convert immunogenic conventional dendritic cells into tolerogenic dendritic cells while inducing its own expression on their cell surface.
Masaaki Toda, Zhifei Shao, Ken D Yamaguchi, Takehiro Takagi, Corina N D'Alessandro-Gabazza, Osamu Taguchi, Hugh Salamon, Lawrence L K Leung, Esteban C Gabazza, John Morser   +9 more
doaj   +1 more source

Tolerogenic dendritic cells protect against acute kidney injury [PDF]

, 2023
Ischemia reperfusion injury is a common precipitant of acute kidney injury that occurs following disrupted perfusion to the kidney. This includes blood loss and hemodynamic shock, as well as during retrieval for deceased donor kidney transplantation ...
Ellis Patrick, Mallett, Andrew J., Natasha M. Rogers, Matigian, Nicholas, Katie Trinh, Harry Robertson, Li, Jennifer S.Y., Raghubar, Arti M., Andrew J. Mallett, Robertson, Harry, Patrick, Ellis, Angus W. Thomson, Quan Nguyen, Nicholas Matigian, Arti M. Raghubar, Jennifer S.Y. Li, Nguyen, Quan, Thomson, Angus W., Rogers, Natasha M., Trinh, Katie   +19 more
core   +1 more source

The role of dendritic cells and their immunometabolism in rheumatoid arthritis

Frontiers in Immunology, 2023
Dendritic cells (DCs) play crucial roles in the pathogenesis of rheumatoid arthritis (RA), a prototypic autoimmune disease characterized by chronic synovitis and joint destruction.
Yuichi Suwa, Yasuo Nagafuchi, Yasuo Nagafuchi, Saeko Yamada, Keishi Fujio   +4 more
doaj   +1 more source

Tolerogenic dendritic cells and their role in transplantation [PDF]

Seminars in Immunology, 2011
The pursuit of clinical transplant tolerance has led to enhanced understanding of mechanisms underlying immune regulation, including the characterization of immune regulatory cells, in particular antigen-presenting cells (APC) and regulatory T cells (Treg), that may play key roles in promoting operational tolerance.
Mohamed, Ezzelarab, Angus W, Thomson
openaire   +2 more sources

Dendritic cell control of tolerogenic responses [PDF]

Immunological Reviews, 2011
Summary:  One of the most fundamental problems in immunology is the seemingly schizophrenic ability of the immune system to launch robust immunity against pathogens, while acquiring and maintaining a state of tolerance to the body’s own tissues and the trillions of commensal microorganisms and food antigens that confront it every day.
Santhakumar, Manicassamy, Bali, Pulendran   +1 more
openaire   +2 more sources

MOLECULAR AND CELLULAR MECHANISMS MEDIATED BY DENDRITIC CELLS INVOLVED IN THE INDUCTION OF TOLERANCE

Медицинская иммунология, 2017
Autoimmune diseases  and  complications  after  transplantation  operations are  major   public health  problem, as they often  lead to deterioration in the quality  of life, reduce  work capacity  and  disability in the  population.
S. V. Sennikov, E. V. Kulikova, N. Yu. Knauer, Yu. N. Khantakova   +3 more
doaj   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Hepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli, Silvia Marchianò, Cristina di Giorgio, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Bianca Fiorillo, Valentina Sepe, Bruno Catalanotti, Chiara Cassiano, Maria Chiara Monti, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +13 more
wiley   +1 more source

Dendritic cells in human renal inflammation - Part II [PDF]

, 2011
Dendritic cells (DCs) are bone marrow-derived professional antigen-presenting cells that act as master regulators of acquired and innate immune responses. Here, we review the available information on their role in human renal inflammation.
Elfriede Noessner, Noessner, Elfriede, Segerer, S., Noessner, E, Stephan Segerer, Nößner, E., Peter J. Nelson, Lindenmeyer, Maja, Segerer, Stephan, Lindenmeyer, M., Lindenmeyer, M, Nelson, P.J., Maja Lindenmeyer, Nelson, Peter J., Segerer, S, Nelson, P J   +15 more
core   +1 more source

Efferocytosis promotes suppressive effects on dendritic cells through prostaglandin E2 production in the context of autoimmunity. [PDF]

PLoS ONE, 2013
INTRODUCTION: Efferocytosis is a crucial process by which apoptotic cells are cleared by phagocytes, maintaining immune tolerance to self in the absence of inflammation.
Irma Pujol-Autonell, Rosa-Maria Ampudia, Raquel Planas, Silvia Marin-Gallen, Jorge Carrascal, Alex Sanchez, Ana Marin, Manuel Puig-Domingo, Ricardo Pujol-Borrell, Joan Verdaguer, Marta Vives-Pi   +10 more
doaj   +1 more source

Dendritic cells in experimental renal inflammation - Part I [PDF]

, 2011
Dendritic cells (DCs) are bone marrow-derived professional antigen-presenting cells that act as master regulators of acquired and innate immune responses.
Elfriede Noessner, Noessner, Elfriede, Segerer, S., Noessner, E, Stephan Segerer, Nößner, E., Peter J. Nelson, Lindenmeyer, Maja, Segerer, Stephan, Lindenmeyer, M., Lindenmeyer, M, Nelson, P.J., Maja Lindenmeyer, Nelson, Peter J., Segerer, S, Nelson, P J   +15 more
core   +1 more source