Results 101 to 110 of about 777,473 (267)

Model certainty in cellular network-driven processes with missing data. [PDF]

open access: yesPLoS Comput Biol, 2023
Irvin MW, Ramanathan A, Lopez CF.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

CAC DPLB MCN: A Distributed Load Balancing Scheme in Multimedia Mobile Cellular Networks

open access: yesFoundations of Computing and Decision Sciences, 2016
The problem of non-uniform traffic demand in different cells of a cellular network may lead to a gross imbalance in the system performance. Thus, the users in hot cells may suffer from low throughput. In this paper, an effective and simple load balancing
Sharma Abhijit   +3 more
doaj   +1 more source

A complete allosteric map of a GTPase switch in its native cellular network. [PDF]

open access: yesCell Syst, 2023
Mathy CJP   +6 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity. [PDF]

open access: yesMol Cell, 2023
Golkowski M   +6 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Enabling Green Cellular Networks: A Review and Proposal Leveraging Software-Defined Networking, Network Function Virtualization, and Cloud-Radio Access Network

open access: yesFuture Internet
The increasing demand for enhanced communication systems, driven by applications such as real-time video streaming, online gaming, critical operations, and Internet-of-Things (IoT) services, has necessitated the optimization of cellular networks to meet ...
Radheshyam Singh   +5 more
doaj   +1 more source

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