Results 91 to 100 of about 488,024 (316)
Scientific DataToll-like receptors (TLRs) are present on the surface of immune cells such as dendritic cells, macrophages, and natural killer cells. TLRs and other pattern recognition receptors (PRRs) are essential for the recognition of microbiological components ...
Doeun Kim +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Ion beam analysis based on cellular nonlinear networks
, 2011 The development of a non- destructive measurement method for ion beam parameters has been treated in various projects. Although results are promising, the high complexity of beam dynamics has made it impossible to implement a real time process control up
Ratzinger, Ulrich +7 more
core +1 more source
Towards neural-symbolic integration: the evolutionary neural logic networks [PDF]
, 2004 This work presents the application of a new methodology for the production of neural logic networks into two real-world problems from the medical domain.
Tsakonas, Athanasios
core +1 more source
Drug repurposing for the treatment of glioblastoma multiforme
Journal of Experimental & Clinical Cancer Research, 2017 Background Glioblastoma Multiforme is the deadliest type of brain tumor and is characterized by very poor prognosis with a limited overall survival.
Claudia Abbruzzese +6 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Maximizing energy-efficiency in multi-relay OFDMA cellular networks
, 2013 This contribution presents a method of obtaining the optimal power and subcarrier allocations that maximize the energy-efficiency (EE) of a multi-user, multi-relay, orthogonal frequency division multiple access (OFDMA) cellular network.
Cheung, Kent Tsz Kan +5 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Impact of Interference Model on Capacity in CDMA Cellular Networks [PDF]
, 2004 This paper discusses an impact of interference model on capacity in CDMA cellular ...
Parvez, Asad, Akl, Robert G.
core
Inactivation of HIPK2 attenuates KRASG12D activity and prevents pancreatic tumorigenesis
Journal of Experimental & Clinical Cancer ResearchBackground Pancreatic ductal adenocarcinoma (PDAC) features KRAS mutations in approximately 90% of human cases and excessive stromal response, termed desmoplastic reaction.
Silvia Sozzi +10 more
doaj +1 more source