Results 111 to 120 of about 488,024 (316)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Ultraviolet (UV) irradiation causes skin wrinkles and decreases elasticity. UV also increases binding between advanced glycation end products (AGEs) and the receptor for AGEs (RAGE), resulting in increased inflammation and activation of NF-κB.
Seyeon Oh +4 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
On the security of software-defined next-generation cellular networks
In the recent years, mobile cellular networks are ndergoing fundamental changes and many established concepts are being revisited. Future 5G network architectures will be designed to employ a wide range of new and emerging technologies such as Software ...
Vasilakis, Vasileios +4 more
core
System level performance of cellular networks utilizing ASA/LSA mechanisms
5 S.Flexible and efficient spectrum usage in cellular communication systems is a key to meet the service demand of forthcoming 4G and 5G networks by 2020. Recent wide-band power measurements in an urban environment show that spectrum below 6 GHz is still
Wirth, T. +4 more
core +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Radio resource allocation in relay based OFDMA cellular networks
PhDAdding relay stations (RS) between the base station (BS) and the mobile stations (MS) in a cellular system can extend network coverage, overcome multi-path fading and increase the capacity of the system.
Xiao, Lin
core
Cooperative Device-to-Device Communications Achieve Maximum Throughput and Maximum Fairness in Cellular Networks [PDF]
Opportunistic schedulers such as MaxRate and Proportional Fair are known for trading off throughput and fairness of users in cellular networks. In this paper we show how to achieve maximum fairness without sacrificing throughput.
Jacko, Peter +2 more
core

