Results 111 to 120 of about 432,489 (267)

Crowdsourced Reconstruction of Cellular Networks to Serve Outdoor Positioning: Modeling, Validation and Analysis. [PDF]

open access: yesSensors (Basel), 2022
Brunello A   +5 more
europepmc   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Unveiling Heterospecific Pollen Deposition in Ranunculus Plants Along a Land‐Use Gradient Through DNA Metabarcoding

open access: yesEcology and Evolution
Animal pollination, the transfer of pollen by animal agents, is essential for plant reproduction. Methods like microscopy and DNA metabarcoding have been used to investigate pollen transport and plant–pollinator interactions.
Susanne Werle   +4 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Glioblastoma metabolomics: uncovering biomarkers for diagnosis, prognosis and targeted therapy

open access: yesJournal of Experimental & Clinical Cancer Research
Glioblastoma (GBM) is characterized by rapid growth, high molecular heterogeneity, and invasiveness. Specific aggressive factors are represented by MGMT promoter methylation, and IDH mutation status.
Susan Costantini   +8 more
doaj   +1 more source

Active T1 transitions in cellular networks. [PDF]

open access: yesEur Phys J E Soft Matter, 2022
Duclut C   +4 more
europepmc   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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