Results 121 to 130 of about 488,024 (316)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Queueing Networks for Vertical Handover

, 2009
PhDIt is widely expected that next-generation wireless communication systems will be heterogeneous, integrating a wide variety of wireless access networks. Of particular interest recently is a mix of cellular networks (GSM/GPRS and WCDMA) and wireless
Song, Guozhi
core  

Poly-D,L-Lactic Acid Filler Increases Hair Growth by Modulating Hair Follicular Stem Cells in Aged Skin

Cells
Age-associated hair loss is primarily driven by decreased function and proliferation of hair follicle stem cells (HFSCs), often exacerbated by increased inhibitory signaling and changes in the stem cell niche.
Seyeon Oh, Jino Kim, Hosung Choi, Hwa Jung Yoo, Kuk Hui Son, Kyunghee Byun   +5 more
doaj   +1 more source

Landscape of nuclear transport receptor cargo specificity

Molecular Systems Biology, 2017
Nuclear transport receptors (NTRs) recognize localization signals of cargos to facilitate their passage across the central channel of nuclear pore complexes (NPCs).
Marie‐Therese Mackmull, Bernd Klaus, Ivonne Heinze, Manopriya Chokkalingam, Andreas Beyer, Robert B Russell, Alessandro Ori, Martin Beck   +7 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Non-Direct Encoding Method Based on Cellular Automata to Design Neural Network Architectures [PDF]

, 2005
Architecture design is a fundamental step in the successful application of Feed forward Neural Networks. In most cases a large number of neural networks architectures suitable to solve a problem exist and the architecture design is, unfortunately, still ...
Gutiérrez Sánchez, Germán, Molina López, José Manuel, Galván, Inés M., Sanchis de Miguel, María Araceli, Isasi, Pedro   +4 more
core  

Middleware for Positioning in Cellular Networks

, 2011
Peer ...
Martín Escalona, Israel, Barceló Arroyo, Francisco, Ciurana Adell, Marc   +2 more
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Interference management in heterogeneous cellular networks [PDF]

, 2013
textHeterogeneous cellular networks (HCNs) – comprising traditional macro base stations (BSs) and heterogeneous infrastructure such as microcells, picocells, femtocells and distributed antennas – are fast becoming a cost-effective and essential way of ...
Xia, Ping
core