Results 51 to 60 of about 6,415,449 (238)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
A low-cost neural sorting network with O(1) time complexity [PDF]
, 2011 [[abstract]]In this paper, we present an O(1) time neural network with O(n1 + var epsilon) neurons and links to sort n data, var epsilon > 0. For large-size problems, it is desirable to have low-cost hardware solutions.
Lin, Shun-Shii;Hsu, Shen-Hsuan
core
Artificial neural networks enable genome-scale simulations of intracellular signaling
Nature Communications, 2022 Many diseases are caused by disruptions to the network of biochemical reactions that allow cells to respond to external signals. Here Nilsson et al develop a method to simulate cellular signaling using artificial neural networks to predict cellular ...
Avlant Nilsson +4 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Frontiers in Physiology, 2020 The molecular regulatory network (MRN) within a cell determines cellular states and transitions between them. Thus, modeling of MRNs is crucial, but this usually requires extensive analysis of time-series measurements, which is extremely difficult to ...
Sang-Mok Choo +2 more
doaj +1 more source
Optimizing Opto-Electronic Cellular Neural Networks Using Bees Swarm Intelligent [PDF]
Engineering and Technology Journal, 2010 This paper presents an application of Bees algorithm to the optimization of cellular neural network for opto-electronics design, where cellular neural networks bees are a large – scale nonlinear analog circuit which processes signals in real time.
Hanan A.R.Akkar
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Simulating land use change by integrating ANN-CA model and landscape pattern indices
Geomatics, Natural Hazards & Risk, 2016 Artificial neural network–cellular automata model has been applied successfully in land use change simulation. However, it has rarely been integrated with landscape pattern indices (LPIs), the embodiment of the spatial heterogeneity of land use.
X. Yang, R. Chen, X.Q. Zheng
doaj +1 more source
Stability Switches in a Cellular Neural Network with Multiple Delays
Journal of Harbin University of Science and Technology, 2019 In order to analyze the effect of timedelay on the stability of the cellular neural network, a cellular neural network with three delays is considered Considering delay as parameter, the stability of the system is investigated Firstly, the resulting ...
ZHANG Ting ting, MA Shu fang
doaj +1 more source
Advances in Difference Equations, 2020 At present, the research on discrete-time Clifford-valued neural networks is rarely reported. However, the discrete-time neural networks are an important part of the neural network theory.
Yongkun Li, Shiping Shen
doaj +1 more source