Results 121 to 130 of about 1,766,854 (293)

Presymptomatic targeted circuit manipulation for ameliorating Huntington’s disease pathogenesis

open access: yesiScience
Summary: Early stages of Huntington’s disease (HD) before the onset of motor and cognitive symptoms are characterized by imbalanced excitatory and inhibitory output from the cortex to striatal and subcortical structures.
Ebenezer C. Ikefuama   +9 more
doaj   +1 more source

Experimental data: 2020 Frontiers in Cellular Neuroscience

open access: yes
As used in the Frontiers 2020 paper https://www.frontiersin.org/journals/cellular-neuroscience/articles/10.3389/fncel.2020.00277 ...
Frances Skinner   +2 more
core  

Clinical and Modifiable Factors Associated With Disability and Relapse in MOGAD: A Multicentre Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang   +23 more
wiley   +1 more source

Baptist Health South Florida Neuroscience News - July 2019

open access: yes, 2019
https://scholarlycommons.baptisthealth.net/bg-bh-neuroscience-news/1000/thumbnail ...
Baptist Health Neuroscience Center
core   +1 more source

Nonlinear Dynamics in Computational Neuroscience

open access: yes, 2019
This book provides an essential overview of computational neuroscience. It addresses a broad range of aspects, from physiology to nonlinear dynamical approaches to understanding neural computation, and from the simulation of brain circuits to the ...
Corinto, Fernando   +3 more
core   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon   +9 more
wiley   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin   +8 more
wiley   +1 more source

Activity dependent modulation of glial gap junction coupling in the thalamus

open access: yesiScience
Summary: Astrocytes and oligodendrocytes in the ventrobasal thalamus are electrically coupled through gap junctions. We have previously shown that these cells form large panglial networks, which have a key role in the transfer of energy substrates to ...
Paula Baum   +9 more
doaj   +1 more source

Neuroscience and Law ::Complicated Crossings and New Perspectives /

open access: yes, 2020
There have been extraordinary developments in the field of neuroscience in recent years, sparking a number of discussions within the legal field. This book studies the various interactions between neuroscience and the world of law, and explores how ...
Errigo, Maria Chiara., D'Aloia, Antonio.
core   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau   +11 more
wiley   +1 more source

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