Results 131 to 140 of about 4,254,953 (206)
Expression of the cellular prion protein by mast cells in the human carotid body. [PDF]
Sweetland GD +4 more
europepmc +1 more source
Iron and Other Metal Ions in Human Health and Disease
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source
The physicochemical nature of the infectious agent in prion diseases creates asignificant challenge for decontamination services. It has been shown to be both resistant tostandard methods of decontamination, used to inactivate viruses and bacteria, and ...
Howlin, Robert
core +1 more source
Among sequenced organisms, the genome of Dictyostelium discoideum is unique in that it encodes for a massive amount of repeat-rich sequences in the coding region of genes.
Felicia N. Williams +5 more
doaj +1 more source
The Exceptions to the Central Dogma of Biology—Bending the Rules and Extending the Scope
ABSTRACT The central dogma is an organizing framework for how information flows in biological systems. First presented in 1957 by Francis Crick in his talk “On Protein Synthesis” as a fundamental hypothesis of how information is transferred from DNA to proteins but not out of proteins, it is now introduced in cell biology textbooks as three sequential ...
Anat Ben‐Zvi
wiley +1 more source
Folding and fibril formation of prions [PDF]
Prions diseases are a group of fatal neurodegenerative disorders called the transmissible spongiform encephalopathies (TSEs), which include bovine spongiform encephalopathy in cattle, scrapie in sheep and Creutzfeldt-Jakob disease (CJD) in humans ...
Gierusz, Leszek A.
core
Papel da proteína prion celular (PrPC) em alterações comportamentais e neuroquímicas associadas ao envelhecimento em camundongo [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2009.A proteína prion celular (PrPC) é uma glicoproteína ancorada aos neurônios que tem sido ...
Rial, Daniel
core
Modular Metalloprotein Nanowires With Semiconductor‐Scale Conductivity and Tunable Redox Behavior
Conductive protein nanowires are built by aligning three different metalloproteins along an ultrastable filament scaffold. The resulting micrometer‐length nanowires reach conductivities of 1.75 S cm−1. Redox behavior is set by the metalloprotein chosen, while conductivity is governed by the spacing the scaffold imposes, making both independently ...
Nga T. Lam +3 more
wiley +1 more source
This study investigates the role of manganese metabolism in Alzheimer's disease (AD) pathogenesis. Using integrated bioinformatics and machine learning, four core manganese‐related diagnostic genes (TSPO, PTBP1, GLO1, ACACB) were identified, showing high diagnostic accuracy. The analysis also revealed significant immune microenvironment alterations and
Shengnan Shu +3 more
wiley +1 more source
ACAT1, Cav-1, and PrP expression in brains and skin fibroblasts from Sarda breed sheep with scrapie-resistant and scrapie-susceptible genotype. [PDF]
Scrapie is an infective ovine neurodegenerative disease; the only identified component of the infectious agent being an aberrant isoform (PrPSc) of the cellular prion protein (PrPC). So far, no means for ante-mortem diagnosis are available for Scrapie as
Claudia Abete +9 more
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