Results 141 to 150 of about 4,254,953 (206)

Cellular Prion Protein Role in Cancer Biology: Is It A Potential Therapeutic Target? [PDF]

Biomedicines, 2022
Yousaf S, Ahmad M, Wu S, Zia MA, Ahmed I, Iqbal HMN, Liu Q, Rehman SU.   +7 more
europepmc   +1 more source

Natural Variation in Drosophila melanogaster Clock PolyQ Length: Geographic Gradients and Functional Properties

Molecular Ecology, Volume 35, Issue 19, October 2026.
ABSTRACT Natural variation in circadian clock genes provides a powerful framework for understanding how organisms respond to environmental heterogeneity. The Clock (Clk) gene encodes a core transcriptional regulator of circadian rhythms and contains a polymorphic polyglutamine (polyQ) tract whose evolutionary significance remains unclear.
Maya Yair, Bettina Fishman, Martin Kapun, Eran Tauber   +3 more
wiley   +1 more source

Endoproteolysis of cellular prion protein by plasmin hinders propagation of prions. [PDF]

Front Mol Neurosci, 2022
Mays CE, Trinh THT, Telling G, Kang HE, Ryou C.   +4 more
europepmc   +1 more source

Safety of frozen paste from blanched, whole migratory locust (Locusta migratoria) as a novel food pursuant to Regulation (EU) 2015/2283

EFSA Journal, Volume 24, Issue 10, October 2026.
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on frozen paste from blanched, whole migratory locusts (Locusta migratoria) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is produced from farmed sub‐adult L. migratoria, which
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Ángeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Margarita Aguilera Gomez, Thomas Frenzel, Francesca Marcon, Harry McArdle, Peter Moldeus, Monika Neuhäuser Berthol, Salvatore Multari, Domenico Azzollini, Karen Ildico Hirsch‐Ernst   +23 more
wiley   +1 more source

An LRP1-binding motif in cellular prion protein replicates cell-signaling activities of the full-length protein. [PDF]

JCI Insight, 2023
Mantuano E, Zampieri C, Azmoon P, Gunner CB, Heye KR, Gonias SL.   +5 more
europepmc   +1 more source

Visualizing α‐synuclein pathology in live brain: A new platform for Parkinson's disease research

Clinical and Translational Medicine, Volume 16, Issue 10, October 2026.
Minhui Yu, Peng Cao
wiley   +1 more source

Emerging roles of the cellular prion protein (PrP^C) and 37/67 kDa laminin receptor (RPSA) interaction in cancer biology. [PDF]

Cell Mol Life Sci, 2023
Limone A, Maggisano V, Sarnataro D, Bulotta S.   +3 more
europepmc   +1 more source

Two mouse models of Alzheimer's disease accumulate amyloid at different rates and have distinct Aβ oligomer profiles unaltered by ablation of cellular prion protein. [PDF]

PLoS One, 2023
Purro SA, Farmer M, Noble E, Sarell CJ, Powell M, Yip D, Giggins L, Zakka L, Thomas DX, Farrow M, Nicoll AJ, Walsh D, Collinge J.   +12 more
europepmc   +1 more source

Beta-endoproteolysis of the cellular prion protein by dipeptidyl peptidase-4 and fibroblast activation protein. [PDF]

Proc Natl Acad Sci U S A, 2023
Castle AR, Kang SG, Eskandari-Sedighi G, Wohlgemuth S, Nguyen MA, Drucker DJ, Mulvihill EE, Westaway D.   +7 more
europepmc   +1 more source

Cellular prion protein levels modulate nigrostriatal vulnerability to α-synuclein oligomers in Parkinson's disease. [PDF]

Front Neurosci
de Souza Júnyor F, Leser FS, de Souza Albuquerque S, de Barros-Telles R, Heimfarth L, da Silva Andrade B, Furtado CM, da Silva LF, Dos Santos FCP, de Oliveira ALSR, Ferreira ST, Braga C, da Fonseca CG, Neves GA, Romão L, Lima FRS.   +15 more
europepmc   +1 more source