TLR7 Mediates HIV-1 Tat-Induced Cellular Senescence in Human Astrocytes. [PDF]
Rezagholizadeh N+5 more
europepmc +1 more source
Dynamic assembly of chromatin complexes during cellular senescence: implications for the growth arrest of human melanocytic nevi [PDF]
Debdutta Bandyopadhyay+7 more
openalex +1 more source
ABSTRACT Introduction The kappa‐free light chain (κ‐FLC) index is known to be highly sensitive and specific for diagnosing multiple sclerosis (MS), while little is understood about lambda (λ)‐FLC. This study assessed the κ‐FLC and λ‐FLC indices in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy.
Michael Levraut+11 more
wiley +1 more source
CDKN2A and matrix metalloproteinases: key regulators of cellular senescence in squamous cell carcinoma. [PDF]
Tian Q+6 more
europepmc +1 more source
Inhibitory role of peroxiredoxin II (Prx II) on cellular senescence
Ying‐Hao Han+5 more
openalex +1 more source
Stage‐Dependent Inhibitory Connectivity in Striatal‐Motor Circuit in Huntington's Disease
ABSTRACT Background Elucidating dysfunctional connectivity patterns among key brain regions in Huntington's disease (HD) underlying progression may have implications for developing treatment and therapeutic evaluation. Objective Explore the relationship between abnormal spontaneous resting‐state activity and atrophy in HD‐specific brain regions and ...
Yinghua Jing+4 more
wiley +1 more source
New insights in cellular senescence: The pituitary model. [PDF]
Herbstein F+8 more
europepmc +1 more source
Cognitive and Patient‐Reported Outcome Measures in LGI‐1‐IgG Autoimmune Encephalitis
ABSTRACT Objective Clinical outcome measures for autoimmune encephalitis (AE) are not yet well defined. Cognitive outcome measures (CogOs) and patient‐reported outcomes (PROs) may capture the symptoms of AE, beyond clinician‐reported outcomes (ClinROs) (the Modified Rankin Scale [mRS] and Clinical Assessment Scale in Autoimmune Encephalitis [CASE ...
Tatchaporn Ongphichetmetha+8 more
wiley +1 more source
Nucleostemin Delays Cellular Senescence and Negatively Regulates TRF1 Protein Stability
Qubo Zhu+2 more
openalex +1 more source
BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach+11 more
wiley +1 more source