Results 161 to 170 of about 1,741,500 (304)

Adoptive cellular therapy prevents reconstitution of myeloid-derived suppressor cells in the glioma tumor microenvironment. [PDF]

Neurooncol Adv
Figg JW, Love C, Stansbury S, Jin D, Francis C, Dean BD, Reid A, Engelbart M, West I, Font LF, Feier D, Ebrahim G, Bessey R, Hilferty D, Yegorov O, Yang C, Long-James K, Mitchell DA, Flores CT.   +18 more
europepmc   +1 more source

Editorial: Cellular Therapies in Cancer [PDF]

Frontiers in Immunology, 2019
Hind Rafei, Rohtesh S. Mehta, Katayoun Rezvani   +2 more
openaire   +3 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

P530: TAGRAXOFUSP IN BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM WITH/WITHOUT CENTRAL NERVOUS SYSTEM INVOLVEMENT AND INTRATHECAL CHEMOTHERAPY AS PRIMARY TREATMENT OR PROPHYLAXIS: AN ITALIAN EXPERIENCE.

HemaSphere, 2022
G. Rivoli, G. Beltrami, A. Raiola, A. Dominietto, M. Riggi, E. Angelucci   +5 more
doaj   +1 more source

Highlighting the CORD-SaFe Trial From Melbourne-Progress Toward Cellular Therapy in Extremely Preterm Newborns. [PDF]

Pediatr Discov
Bhatt A, Nimbalkar S, Patel D, Pujara R.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Cancer immunotherapy insights: key takeaways from the ADSCC bone marrow and cellular therapy congress 2024. [PDF]

Front Immunol
Suárez Formigo GM, Mazorra Z, Olexen C, Menéndez T, Abdel Hadi L, Handgretinger R, Bencomo Hernandez AA, El Najjar I, Coukos G, Sabzevari H, Bollard C, Couriel D, Wald D, Hamieh M, Briones J, Al Kaabi F, Ventura-Carmenate Y.   +16 more
europepmc   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Cellular and gene therapy

HemaSphere, 2019
openaire   +3 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source