Results 141 to 150 of about 1,093,681 (262)

Gene Therapy for Sickle Cell Disease: Practice Recommendations from the American Society for Transplantation and Cellular Therapy and the International Society for Cell & Gene Therapy. [PDF]

Transplant Cell Ther
Sharma A, Kassim A, Thompson A, Williams DA, Liu HD, Boelens JJ, LaBelle JL, Tisdale J, de la Fuente J, Kanter J, Krishnamurti L, Pecker LH, Walters MC, Eapen M, Porteus M, Bhatia M, Soni S, Corbacioglu S, John TD, Cancio MI.   +19 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Fertility management and outcomes after CAR T-cell therapy: an international survey from the Cellular Therapy and Immunobiology working party of the European Society for Blood and Marrow Transplantation. [PDF]

EClinicalMedicine
Orofino G, Sánchez-Ortega I, Mota JS, Aroldi A, Castilla-Llorente C, Bigenwald C, Dalle JH, Yacouben K, Di Blasi R, Galli E, Grandage V, Palasciano A, Bacon L, Franke GN, Fandrei D, Merz M, George L, Lopez-Corral L, Hecker JS, Mannina D, Bramanti S, Martin Gonzalez JA, Martínez-Cibrian N, Petersen SL, Polgarova K, Protheroe R, Richardson D, Ram R, Elias S, von Tresckow B, Stölzel F, Streiss I, Vallet N, Knippenberg J, Tomas AA, Pagliuca S, Malard F, Kuball J, Ruggeri A.   +38 more
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

SP05 | MARIBAVIR AS ANTI-CYTOMEGALOVIRUS TREATMENT IN REFRACTORY OR RESISTANT DISEASES IN A NON-TRANSPLANT SETTING

Haematologica
Introduction: CMV infection can be life-threatening in immunocompromised patients. In the setting of allo-HSCT, different treatment strategies exist for refractory or resistant CMV disease.
U. Pizzano, G. De Cicco, D. Schiavo, E. Scarpa, M. Stanzani.   +4 more
doaj  

Remestemcel-L-rknd (Ryoncil): the first approved cellular therapy for steroid-refractory acute GVHD. [PDF]

Blood
Etra A, Ferrara JLM, Levine JE.
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Corrigendum to: Current Activity Trends and Outcomes in Hematopoietic Cell Transplantation and Cellular Therapy - A Report from the CIBMTR, Transplantation and Cellular Therapy, 31:8, August 2025, 505-532; Article Number: JTCT-S-25-00377. [PDF]

Transplant Cell Ther
Spellman SR, Xu K, Oloyede T, Ahn KW, Akhtar OS, Bolon YT, Broglie L, Bloomquist J, Bupp C, Chen M, Devine SM, Jurdi NE, Hamadani M, Hengen M, Huppler AH, Jaglowski S, Kuxhausen M, Lee SJ, Moskop A, Page KM, Pasquini MC, Pérez WS, Phelan R, Rizzo D, Saber W, Stefanski HE, Steinert P, Tuschl E, Visotcky A, Vogel R, Auletta JJ, Shaw BE, Allbee-Johnson M.   +32 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Reply to "Finding the middle way: rethinking cGMP for sterility testing of cellular therapy products in minimal manipulation settings". [PDF]

J Clin Microbiol
Lau AF.
europepmc   +1 more source