Results 101 to 110 of about 2,335,939 (309)
Cellular uptake of nanospheres.
, 2016 Cellular uptake of nanospheres. Confocal microscopic images showing cellular uptake of PLGA or PLGA/DC-Chol nanospheres tagged with 6-coumarin (green) by mNSCs after 6 h (Top) or 24 h (Bottom) of incubation. Nuclei were stained with DAPI (blue) Scale bar
Yeomin Yun (2175404) +4 more
core +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Further Explorations of Cellular Uptake of Radioactivity [PDF]
Journal of Nuclear Medicine, 2008 It is widely recognized in the field of internal emitter therapy that radiopharmaceuticals are distributed nonuniformly within tissues of localization, and this nonuniformity extends to all spatial levels—organs, suborgans, multicellular clusters, single cells, and even subcellular ...
openaire +2 more sources
The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles
, 2012 Eleonore FröhlichCenter for Medical Research, Medical University of Graz, Graz, AustriaAbstract: Many types of nanoparticles (NPs) are tested for use in medical products, particularly in imaging and gene and drug delivery. For these applications,
Fröhlich E
core
International Journal of Nanomedicine, 2012 Sasha H Bakhru,1 Eda Altiok,2 Christopher Highley,1 Daniel Delubac,1 Joseph Suhan,2 T Kevin Hitchens,2 Chien Ho,2 Stefan Zappe11Department of Biomedical Engineering, 2Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA ...
Bakhru SH +7 more
doaj
Mechanism of cellular uptake of genotoxic silica nanoparticles
Particle and Fibre Toxicology, 2012 Mechanisms for cellular uptake of nanoparticles have important implications for nanoparticulate drug delivery and toxicity. We have explored the mechanism of uptake of amorphous silica nanoparticles of 14 nm diameter, which agglomerate in culture medium ...
Mu Qingshan +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source