Results 161 to 170 of about 648,939 (326)

Resistome flow in global landfill systems

open access: yesiMetaOmics, EarlyView.
Global landfill systems represent key hubs of resistome, serving as dynamic reservoirs and amplifiers through plasmid‐driven gene mobility. Waste flows and environmental pathways sustain the transboundary resistome networks, accelerating resistance dissemination across ecosystems.
Wenqing Hong   +12 more
wiley   +1 more source

The role of the gut microbiome in the regulation of high‐altitude adaptation

open access: yesiMeta, EarlyView.
This study is the first to elucidate mechanisms of high‐altitude adaptation from the perspective of the rumen ecosystem by using indigenous yaks and Holstein cows that have lived at high altitude since birth as comparative models. Through a systematic comparison of their rumen ecology using multi‐omics approaches—including rumen metagenomics ...
Xinyu Zhang   +6 more
wiley   +1 more source

STUDY OF ENZYMATIC HYDROLYSIS OF MILD PRETREATED LIGNOCELLULOSIC BIOMASSES

open access: yesBioResources, 2012
The effect of mild acidic and alkaline pretreatments of various plant biomasses on their enzymatic hydrolysis has been studied. The yield of reducing sugars and utilization rate of the biomass were used as reliable characteristics of enzymatic ...
Michael Ioelovich,, Ely Morag
doaj  

Microbial metabolites in tumor epigenetic regulation

open access: yesiMeta, EarlyView.
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang   +31 more
wiley   +1 more source

Adipose‐derived small extracellular vesicles exacerbate microvascular dysfunction in heart failure with preserved ejection fraction via mmu‐miR‐582‐3p‐mediated Rap1b suppression

open access: yesInterdisciplinary Medicine, EarlyView.
This study reveals that small extracellular vesicles (sEVs) from visceral fat compromise coronary microcirculation in a mouse model of heart failure with preserved ejection fraction (HFpEF). The SGLT2 inhibitor canagliflozin emerges as a therapeutic strategy, improving cardiac function and endothelial health.
Lu Chen   +12 more
wiley   +1 more source

Stimuli‐responsive hydrogels: An intelligent tool for wound management

open access: yesInterdisciplinary Medicine, EarlyView.
For chronic and complex wounds, this review focuses on intelligent hydrogels capable of responding to wound microenvironmental cues (e.g., pH, enzymes) or external stimuli (e.g., light, electricity). These advanced materials enable the dynamic regulation of drug release and real‐time monitoring of healing progression, thereby offering innovative ...
Debin Zheng   +10 more
wiley   +1 more source

Lignin Removal in Subcellular Location of Poplar Cell Wall During Pretreatment Significantly Impacts Cellulose Digestibility. [PDF]

open access: yesACS Sustain Chem Eng
Zhang J   +9 more
europepmc   +1 more source

Cellulose hydrolysis by Clostridium thermocellum is agnostic to substrate structural properties in contrast to fungal cellulases [PDF]

open access: yes, 2019
Bhagia, Samarthya   +9 more
core  

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni   +6 more
wiley   +1 more source

Impacts of Biostimulants on Nitrous Oxide Emissions and the Soil Microbiome

open access: yesJournal of Plant Nutrition and Soil Science, EarlyView.
Soil incubation experiment examining the influence of biostimulants on greenhouse gas emissions and the soil microbiome in fertilized soils. ABSTRACT Background Overapplication of nitrogenous fertilizer and enhanced microbial activity in agricultural soils are drivers of increasing greenhouse gas emissions.
Conor Blunt   +4 more
wiley   +1 more source

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