Results 111 to 120 of about 1,858 (240)

Triterpenic Acids as Non-Competitive α-Glucosidase Inhibitors from Boswellia elongata with Structure-Activity Relationship: In Vitro and In Silico Studies

open access: yesBiomolecules, 2020
Fourteen triterpene acids, viz., three tirucallane-type (1–3), eight ursane-type (4–11), two oleanane-type (12, 13) and one lupane type (21), along with boswellic aldehyde (14), α-amyrine (15), epi-amyrine (16), straight chain acid (17), sesquiterpene ...
Najeeb Ur Rehman   +8 more
doaj   +1 more source

Sandensolide Induces Oxidative Stress-Mediated Apoptosis in Oral Cancer Cells and in Zebrafish Xenograft Model

open access: yesMarine Drugs, 2018
Presently, natural sources and herbs are being sought for the treatment of human oral squamous cell carcinoma (OSCC) in order to alleviate the side effects of chemotherapy.
Chung-I Yu   +8 more
doaj   +1 more source

Terpenoid constituents from leaves of Guarea kunthiana [PDF]

open access: yes, 2004
Das folhas de Guarea kunthiana foram obtidos um novo diterpeno com esqueleto do tipo caurano (ent-caur-16-eno-2-ona), além de oito diterpenos (ent-caur-16-eno, ent-3a- e 3b-hidroxicaur-16-eno, kolavelool, kolavenol, kolavenal, ent-13-epi-óxido de manoíla
Bazzo, Rita de Cássia   +4 more
core   +1 more source

Sulforaphane exerts anti-angiogenesis effects against hepatocellular carcinoma through inhibition of STAT3/HIF-1α/VEGF signalling [PDF]

open access: yes, 2017
Angiogenesis plays an important role in hepatocellular carcinoma (HCC), the inhibition of which is explored for cancer prevention and treatment. The dietary phytochemical sulforaphane (SFN) is known for its anti-cancer properties in vitro and in vivo ...
Akbareian, Sophia   +6 more
core   +2 more sources

Photochemical formation of intricarene [PDF]

open access: yes, 2014
Sunlight is the ultimate driver of biosynthesis but photochemical steps late in biosynthetic pathways are very rare. They appear to play a role in the formation of certain furanocembranoids isolated from Caribbean corals.
Kimbrough, Thomas J.   +5 more
core   +1 more source

Populeuphrines A and B, two new cembrane diterpenoids from the resins of Populus euphratica

open access: yesNatural Product Research, 2019
Two new cembrane diterpenoids, named populeuphrines A and B (1 and 2), together with three known analogues (3–5) were isolated from the resins of Populus euphratica. The planar structures and relative configurations of 1 and 2 were elucidated by detailed
Kai-Xin Liu   +6 more
semanticscholar   +1 more source

An unreported bis-abeo cembrane-type diterpenoid with antioxidative and anti-lipoxygenase activities from the muricid gastropod mollusc Chicoreus ramosus

open access: yesNatural Product Research, 2018
The chemical analyses of ethyl acetate-methanol (EtOAc-MeOH) extract of muricid gastropod mollusk, Chicoreus ramosus from the southeastern coast of Indian peninsular led to the identification of unprecedented cembrane-type diterpenoid, which was ...
K. Chakraborty, Soumya Salas, Minju Joy
semanticscholar   +1 more source

Chabrolene, a Novel Norditerpene from the Bornean Soft Coral Nephthea sp. [PDF]

open access: yes, 2018
Soft corals are often the research interest organism due to their structural diverse secondary metabolites with wide spectrum of biological activities range from antibacterial to anticancer potentials.
Charles Santhanaraju Vairappan   +3 more
core  

Anticancer diterpenes of African natural products: Mechanistic pathways and preclinical developments [PDF]

open access: yes
64 p.Background: The African continent is home to five biodiversity hotspots, boasting an immense wealth of medicinal flora, fungi and marine life. Diterpenes extracted from such natural products have compelling cytotoxic activities that warrant further ...
Almeida Rosatella, Andreia de   +8 more
core   +1 more source

Genotoxicity and 28-day repeated dose oral toxicity study of ovatodiolide in rats

open access: yesToxicology Reports, 2021
Ovatodiolide is a bioactive cembrane-type diterpenoid isolated from Anisomeles indica (L.) Kuntze. It has been proven that ovatodiolide is anti-inflammatory, anti-tumorigenic, anti-melanogenic and attenuates asthma by regulating signaling pathways.
Jing-Chun Chen   +3 more
doaj  

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