Results 121 to 130 of about 873 (161)

New Cembranes from Cleome spinosa

Journal of Natural Products, 2003
Examination of the aerial portions of Cleome spinosa yielded five new cembranes, named cleospinols A (1), B (3), C (4), and D (5), and the 3'-hydroxy-iso-pentan-10-oate ester of cleospinol A (2). The cleospinols were determined to be derivatives of 10,13-dihydroxy-4,12-dimethyl-1-(1-methylethenyl)-11(E)-cyclotetradecene on the basis of spectroscopic ...
Dwight O, Collins, William F, Reynolds, Paul B, Reese   +2 more
openaire   +2 more sources

Intermediates in the Synthesis of Cembrane Diterpenes. I

Acta Crystallographica Section C Crystal Structure Communications, 1997
The molecular structure of rac-(1R,2R,3S,7S)-3-hydroxy-5-isopropyl-2-methyltricyclo[8.4.0.0 2,7 ]tetradeca-4,9-dien-6-one, C 18 H 26 O 2 , has an all-cis ring-fusion tricyclic structure, with an overall distorted hemispherical conformation (the hydroxyl group is opposite the other substituents).
I. Caracelli, J. Iulek, A. Neves, I. Vencato, F. Silva, T. J. Brocksom, J. Zukerman-Schpector   +6 more
openaire   +1 more source

Cytotoxic Cembrane Diterpenoids

2014
Cembrane-type diterpenoids are a large and structurally varied group of natural products isolated from both terrestrial and marine organisms. From a biomedical perspective, cytotoxicity is the most remarkable property of this class of diterpenoids, respresented by sarcophytol A.
Bin Yang, Juan Liu, Junfeng Wang, Shengrong Liao, Yonghong Liu   +4 more
openaire   +1 more source

Cembrane Diterpenes from the Gorgonian Leptogorgia laxa

Journal of Natural Products, 2008
The new cembrane diterpenes leptodienone A (2) and leptodienone B (3) and the known compounds lopholide, lophodiol B, lophodione, and lophotoxin (1) have been isolated from the gorgonian Leptogorgia laxa collected in the Gulf of California. The structures of the new metabolites have been established by spectroscopic techniques.
María J, Ortega, Eva, Zubía, M Carmen, Sánchez, J Luis, Carballo   +3 more
openaire   +2 more sources

Cembrane Diterpenes Chemistry and Biological Properties

Current Organic Chemistry, 2012
Cembrane-type diterpenoids are a large and structurally varied group of natural products isolated from both terrestrial and marine organisms. The present paper reviews all the metabolites of cembrane diterpenes, reported up to 2010. The natural products discussed in this review can be divided into several different structural families featuring a ...
Bin Yang, Xue-Feng Zhou, Xiu-Ping Lin, Juan Liu, Yan Peng, Xian-Wen Yang, Yonghong Liu   +6 more
openaire   +1 more source

Cembrane Diterpenes from the Gorgonian Lophogorgia peruana

Journal of Natural Products, 2006
The chemical study of the gorgonian Lophogorgia peruana collected at the Gulf of California has led to the isolation of the new diterpenes lophodienone (2), lophodiol A (3), lophodiol B (4), 17-acetoxylophotoxin (5), 15,16-epoxylophotoxin (6), 17-acetoxy-15,16-epoxylophotoxin (7), and isoepoxylophodione (8), together with the known compounds lophotoxin
M Carmen, Sanchez, María J, Ortega, Eva, Zubía, J Luis, Carballo   +3 more
openaire   +2 more sources

Single solution phase conformation of new antiproliferative cembranes

Tetrahedron, 1999
Two new cembranes (2 and 3) have been isolated from thr extract of the Antarctic sponge Lissodendoryx flabellata. Their structural elucidation has been performed by spectroscopic techniques, whereas the absolute configuration of the secondary carbinolic center was inferred by Mosher's method. The absolute stereochemistry of the second asymmetric carbon,
Angelo Fontana, Maria Letizia Ciavatta, Pietro Amodeo, Guido Cimino   +3 more
openaire   +5 more sources

Cembrane-type diterpenoids from the Chinese liverwort Chandonanthus birmensis

Phytochemistry, 2022
A chemical investigation of the Chinese liverwort Chandonanthus birmensis Steph identified five undescribed cembrane-type diterpenoids, together with six known cembrane diterpenes, one fusicoccane-type diterpenoid, and a dolabellane-type diterpenoid.
Xue, Wang, Lilin, Qian, Yanan, Qiao, Xueyang, Jin, Jinchuan, Zhou, Shuangzhi, Yuan, Jiaozhen, Zhang, Chunyang, Zhang, Hongxiang, Lou   +8 more
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Some new cembrane derivatives of marine origin

Tetrahedron, 1974
Abstract The isolation and structural determination of several cembrane derivatives (2–7) isolated from the soft-bodied coral sarcophytum glaucum- is reported. The various compounds can be divided into cembranolids, cembranes containing the dihydrofurane moiety, and correlated alcohols. The stereochemistry at C-1, as well as that of the epoxide ring,
Y. Kashman, E. Zadock, L. Néeman
openaire   +1 more source

Bioactive cembrane diterpenoids from the gum resin of Boswellia carterii

Fìtoterapìâ, 2020
Eight new cembrane-type diterpenoids, boscartins AP-AW (1-8) were obtained from the gum resin of Boswellia carterii. Among which, six ones (2-7) were isomers, with one hydroxy group and two double bonds migrating along the carbocycle. The structures were elucidated by spectroscopic examination. All isolates were evaluated for anti-inflammatory activity
Xiao Wang, Jinqian Yu, Yanling Geng
exaly   +3 more sources