Investigating the spatiotemporal expression of CBTS genes lead to the discovery of tobacco root as a cembranoid-producing organ [PDF]
Frontiers in Plant ScienceTobacco cembranoids, known for their anti-insect and antifungal properties, were shown to be mainly present on the surface of leaves and flowers, being biosynthesized by their trichomes.
Yongmei Du, Du Yongmei, Liao Zhihua
exaly +4 more sources
Synthesis of cembratriene-ol and cembratriene-diol in yeast via the MVA pathway [PDF]
Microbial Cell Factories, 2021 Background Cembranoids are one kind of diterpenoids with multiple biological activities. The tobacco cembratriene-ol (CBT-ol) and cembratriene-diol (CBT-diol) have high anti-insect and anti-fungal activities, which is attracting great attentions for ...
Yu Zhang +9 more
doaj +2 more sources
Cembranoids from Octocoral Lobophytum crassum (von Marenzeller, 1886) [PDF]
Marine Drugs, 2021 Two cembranoids, including a new compound, lobocrassin I (1), as well as a known analogue, lobohedleolide (2), were obtained by solvent extraction from octocoral Lobophytum crassum. This study employed a spectroscopic approach to establish the structures
Yao-Tsung Yeh +9 more
doaj +2 more sources
A Review on Bioactivities of Tobacco Cembranoid Diterpenes
Biomolecules, 2019 Cembranoids are carbocyclic diterpenes comprising four isoprene units and are natural products with a parent skeleton consisting of a 14-membered ring.
Liu Xinmin, Hongbo Zhang, Ning Yan
exaly +3 more sources
Cembranoid Diterpenes from South China Sea Soft Coral Sarcophyton crassocaule [PDF]
Marine DrugsCembranoid diterpenes are characteristic compounds of soft corals with diverse structures and significant activities, making them an important source of drug lead compounds.
Hanyang Peng +9 more
doaj +2 more sources
Exploration of anti‐leukemic effect of soft coral‐derived 13‐acetoxysarcocrassolide: Induction of apoptosis via oxidative stress as a potent inhibitor of heat shock protein 90 and topoisomerase II [PDF]
Kaohsiung Journal of Medical Sciences, 2023 13‐Acetoxysarcocrassolide (13‐AC) is a marine cembranoid derived from the aquaculture soft coral of Lobophytum crassum. The cytotoxic effect of 13‐AC against leukemia cells was previously reported but its mechanism of action is still unexplored.
Hsien‐Kuo Chin +10 more
doaj +2 more sources
Secocrassumol, a seco-Cembranoid from the Dongsha Atoll Soft Coral Lobophytum crassum
Marine Drugs, 2014 Chemical investigations on the Dongsha Atoll soft coral Lobophytum crassum led to the purification of a new seco-cembranoid, secocrassumol. The structural elucidation was established by extensive NMR, HRESIMS and CD data.
Shang-Kwei Wang +2 more
exaly +3 more sources
Blue Biotechnology: Computational Screening of Sarcophyton Cembranoid Diterpenes for SARS-CoV-2 Main Protease Inhibition [PDF]
Marine Drugs, 2021 The coronavirus pandemic has affected more than 150 million people, while over 3.25 million people have died from the coronavirus disease 2019 (COVID-19).
Mahmoud A. A. Ibrahim +15 more
doaj +2 more sources
Isosarcophytoxide Derivatives with a 2,5-Dihydrofuran Moiety from the Soft Coral Sarcophyton cinereum [PDF]
Molecules, 2023 The present chemical investigation on the organic extract of the soft coral Sarcophyton cinereum has contributed to the isolation of four new cembranoids: 16β- and 16α-hydroperoxyisosarcophytoxides (1 and 2), 16β- and 16α-methoxyisosarcophytoxides (3 and
Chih-Hua Chao +9 more
doaj +2 more sources
Antibacterial Methyl Ester Cembranoids from the Soft Coral Sarcophyton ehrenbergi and Their Structural Elucidation [PDF]
Marine DrugsSix previously undescribed methyl ester cembranoids, namely sarcoehrenolides L–Q (1–6), along with three known related ones (7–9), were isolated from the soft coral Sarcophyton ehrenbergi collected off Weizhou Island in the South China Sea.
Meng-Jun Wu +4 more
doaj +2 more sources