Results 31 to 40 of about 724 (183)
Inhibition of Soluble Epoxide Hydrolase by Cembranoid Diterpenes from Soft Coral Sinularia maxima: Enzyme Kinetics, Molecular Docking, and Molecular Dynamics. [PDF]
Mar DrugsSoluble epoxide hydrolase (sEH) is essential for converting epoxy fatty acids, such as epoxyeicosatrienoic acids (EETs), into their dihydroxy forms.
Phong NV +5 more
europepmc +2 more sources
Food and Energy Security, Volume 12, Issue 5, September 2023., 2023 Abstract As one of the most destructive pests, aphids cause significant damage on various agricultural and horticultural crops. Recently, melatonin has been shown to enhance plant resistance to aphids; however, the underlying mechanisms remain unclear.
Zhuangzhuang Su +10 more
wiley +1 more source
Anti-Inflammatory Cembranoids from a Formosa Soft Coral Sarcophyton cherbonnieri
Marine Drugs, 2020 The present investigation on chemical constituents of the soft coral Sarcophyton cherbonnieri resulted in the isolation of seven new cembranoids, cherbonolides F–L (1–7).
Chia-Chi Peng +4 more
doaj +1 more source
Chemistry – A European Journal, Volume 28, Issue 63, November 11, 2022., 2022 The convergent total synthesis of furanocembranoids (FC) molestin E, ent‐sinulacembranolide A and ent‐sinumaximol A was achieved in 20–21 steps in the longest linear sequence (LLS). Building blocks were coupled through a furan metalation sequence and macrocycle formation was effected by Shiina lactonisation. The primary target molestin E was elaborated
Oskar Hoff +4 more
wiley +1 more source
Oxygenating Biocatalysts for Hydroxyl Functionalisation in Drug Discovery and Development
ChemMedChem, Volume 17, Issue 12, June 20, 2022., 2022 C−H bond oxyfunctionalisation is a significant challenge in organic synthetic chemistry. In drug discovery and development, exploiting biocatalytic methods which can introduce hydroxyl groups deftly with high selectivity, under mild conditions, is of paramount interest.
Sacha N. Charlton, Martin A. Hayes
wiley +1 more source
Pharmaceuticals, 2022 As one of the most characteristic ingredients of glandular trichome secretions from Nicotiana tabacum L. (tobacco), natural cembrenediols, namely, (1S,2E,4S,6R,7E,11E)-2,7,11-cembratriene-4,6-diol (α-cembrenediol/α-CBD) and its C-4 epimer (β-cembrenediol/
Kuo Xu +6 more
doaj +1 more source
The chemotype core collection of genus Nicotiana
The Plant Journal, Volume 110, Issue 5, Page 1516-1528, June 2022., 2022 SUMMARY Sustainable production of chemicals and improving these biosources by engineering metabolic pathways to create efficient plant‐based biofactories relies on the knowledge of available chemical/biosynthetic diversity present in the plant. Nicotiana species are well known for their amenability towards transformation and other new plant breeding ...
Margit Drapal +2 more
wiley +1 more source
A new cembranoid from the Red Sea soft coral Sarcophyton acutum [PDF]
, 2022 The Red Sea soft coral Sarcophyton acutum ethyl acetate extract has afforded one new cembranoid; sarcacutumolid A (1), along with six known metabolites have been isolated from S. acutum for the first time (2-7).
Mohamed A. M. Atia (12042210) +8 more
core +1 more source
Marine Drugs, 2020 Chemical investigation of the marine soft coral Sarcophyton tenuispiculatum resulted in the isolation of a 1,4-dihydrobenzoquinone, sarcotenuhydroquinone (1), three new cembranoids, sarcotenusenes A‒C (2‒4), and ten previously reported metabolites 5–14 ...
Tzu-Yin Huang +7 more
doaj +1 more source
Cembranoids from the cultured soft coral <i>Sinularia sandensis</i>. [PDF]
RSC AdvThis study reports the isolation and characterization of two novel diterpenoids, norcembranoid 10- epi -dehydrogyrosanolide E (1) and cembranoid 8- epi -flexibilisolide G (2), from the cultured soft coral Sinularia sandensis
Lai KH +7 more
europepmc +3 more sources