Results 41 to 50 of about 724 (183)

Phylogeny, Phytomedicines, Phytochemistry, Pharmacological Properties, and Toxicity of Croton gratissimus Burch (Euphorbiaceae)

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2022, Issue 1, 2022., 2022
Croton gratissimus is an important plant in Africa setup and across the globe for its ethnomedicinal uses in managing a wide range of diseases. Its phylogeny, pharmacological properties, ethnomedicinal uses, phytochemistry, and cytotoxicity have been highlighted in various articles and journals.
Kirkland Dingili Magwilu, Joseph Mwanzia Nguta, Isaac Mapenay, Dorine Matara, Srinivas Mutalik   +4 more
wiley   +1 more source

Enzymkatalysierte späte Modifizierungen: Besser spät als nie

Angewandte Chemie, Volume 133, Issue 31, Page 16962-16993, July 26, 2021., 2021
Späte Modifizierungen sind unerlässlich für die Diversifizierung von Verbindungen in der Synthese. Da Enzyme effiziente Werkzeuge für milde, Katalysator‐kontrollierte Funktionalisierungen bieten, sind neue biokatalytische Methoden für eine große Fülle orthogonaler Reaktionen entstanden.
Elvira Romero, Bethan S. Jones, Bethany N. Hogg, Arnau Rué Casamajo, Martin A. Hayes, Sabine L. Flitsch, Nicholas J. Turner, Christian Schnepel   +7 more
wiley   +1 more source

Actions of octocoral and tobacco cembranoids on nicotinic receptors [PDF]

Toxicon, 2009
Nicotinic acetylcholine receptors (AChRs) are pentameric proteins that form agonist-gated cation channels through the plasma membrane. AChR agonists and antagonists are potential candidates for the treatment of neurodegenerative diseases. Cembranoids are naturally occurring diterpenoids that contain a 14-carbon ring.
Ferchmin, P. A., Pagán, Oné R., Ulrich, Henning, Szeto, Ada C., Hann, Richard M., Eterović, Vesna A.   +5 more
openaire   +3 more sources

Studies of Australian soft corals. XVIII. Further cembranoid diterpenes from soft corals of the genus Sarcophyton [PDF]

, 1980
The structure of two new cembranoid diterpenes, (E,E,E)-7,8-epoxy-1- isopropyl-4,8,12-trimethylcyclotetradeca-1,3,11-triene (2) and (E,E,E)- 7,8-epoxy-1-isopropenyl-4,8,12-trimethylcyclotetradeca-1,3,11-triene (4), are reported.
JC Coll, SJ Mitchell, BF Bowden
core   +1 more source

Bioactive Natural, Biocatalytic, and Semisynthetic Tobacco Cembranoids

Planta Medica, 2010
The two major Nicotiana tabacum tobacco cembranoids, (1 S,2 E,4 R,6 R,7 E,11 E)-2,7,11-cembratriene-4,6-diol (1) and its C-4 epimer, exhibit a wide range of interesting biological activities. Although the tumorigenesis inhibition activity of tobacco cembranoids have been known since the mid 1980's, only a limited number of investigations have targeted ...
Hany N, Baraka, Mohammad A, Khanfar, John C, Williams, Emad M, El-Giar, Khalid A, El Sayed   +4 more
  +6 more sources

Sarcophyolides B–E, New Cembranoids from the Soft Coral Sarcophyton elegans

Marine Drugs, 2013
Four new cembrane-type diterpenoids, sarcophyolides B–E (1–4), along with 11 known analogues were isolated from the soft coral Sarcophyton elegans. The structures of new compounds 1–4 were established on the basis of spectroscopic analysis and chemical ...
Leen van Ofwegen, Peter Proksch, Dong Liu, Wei Bie, Wei Chen, Zhifang Xi, Wenhan Lin   +6 more
doaj   +1 more source

Cembranoids of Soft Corals: Recent Updates and Their Biological Activities. [PDF]

Nat Prod Bioprospect, 2021
Abstract Soft corals are well-known as excellent sources of marine-derived natural products. Among them, members of the genera Sarcophyton, Sinularia, and Lobophytum are especially attractive targets for marine natural product research.
Nurrachma MY, Sakaraga D, Nugraha AY, Rahmawati SI, Bayu A, Sukmarini L, Atikana A, Prasetyoputri A, Izzati F, Warsito MF, Putra MY.   +10 more
europepmc   +6 more sources

Studies of Australian soft corals. XXIV. Two cembranoid diterpenes from the soft coral Sinularia facile [PDF]

, 1981
Extraction of the soft coral Sinularia facile afforded two cembranoid diterpenes whose structures and absolute configurations have been determined as (1R,4R,2E,7E,11E)-cembra-2,7,11-trien-4-ol (1) and (1R,3S,4S,7E,11E)-3,4-epoxycembra-7,11,15-triene (2).
JC Coll, R Kazlauskas, SJ Mitchell, BF Bowden   +3 more
core   +1 more source

Polycyclic Furanobutenolide-Derived Cembranoid and Norcembranoid Natural Products: Biosynthetic Connections and Synthetic Efforts [PDF]

, 2017
The polycyclic furanobutenolide-derived cembranoid and norcembranoid natural products are a family of congested, stereochemically complex, and extensively oxygenated polycyclic diterpenes and norditerpenes.
Robert A. Craig, Stoltz, Brian M., Brian M. Stoltz, Craig, Robert A., II   +3 more
core   +1 more source

Logic Structure Determination (LSD) as a Computer Assisted Structure Elucidation (CASE) for Molecular Structure Determination of Cytotoxic Cembranoids from Soft Coral

Squalen, 2016
Indonesian tropical soft corals are valuable resources that produce pharmacological cytotoxic cembranoids. However,  the manual structure determination in these compounds requires adequate knowledge of organic chemistry.
Hedi Indra Januar, Neviaty Putri Zamani, Dedi Soedharma, Ekowati Chasanah   +3 more
doaj   +1 more source