Results 91 to 100 of about 1,087 (181)

Long-Term Efficacy and Tolerability of Cenobamate in Clinical Practice: A Retrospective Observational Study

Annals of Indian Academy of Neurology
Background and Objectives: Cenobamate (CNB) was approved in the US in 2020 and showed 12% seizure freedom in drug-resistant epilepsy (DRE) in pivotal trials.
Shubhi Agrawal, Batool A Hussain, Kiran M Kanth   +2 more
doaj   +1 more source

Cenobamate as add-on treatment in ultra-refractory focal epilepsy:Real-world results from The Danish Epilepsy Centre, Dianalund, Denmark

Objectives: At The Danish Epilepsy Centre, Dianalund, Denmark, we aimed to assess the long-term efficacy, tolerability profile, and influence on concomitant antiseizure medications (ASMs) of cenobamate as an add-on treatment in patients with ultra ...
Møller, Rikke S., Rubboli, Guido, Juhl, Stefan, Mieszczanek, Katarzyna M., Gjerulfsen, Cathrine E., Spanilá, Lucie, Thygesen, Kristin S., Pavbro, Agnieszka   +7 more
core   +1 more source

Treatment simplification to optimize cenobamate effectiveness and tolerability: A real‐world retrospective study in Spain

Epilepsia Open
Objective This study aimed to explore the impact of co‐antiseizure medication (co‐ASM) optimization on the effectiveness and tolerability of adjunctive cenobamate (CNB) in patients with drug‐resistant epilepsy in a real‐world setting.
Juan Jesús Rodríguez‐Uranga, Juan María Sánchez‐Caro, Roshan Hariramani Ramchandani   +2 more
doaj   +1 more source

Cenobamate

American Journal of Health-System Pharmacy, 2020
openaire   +1 more source

A Multiscale Structural, Pharmacokinetic–Pharmacodynamic and Systems Pharmacology Framework Exploring a Plausible Interaction Between Cenobamate and Low-Dose Clobazam in Drug-Resistant Epilepsy

Drug-resistant epilepsy (DRE) remains a major therapeutic challenge despite the availability of numerous antiseizure medications (ASMs). Clinical observations suggest that, in some patients, the addition of low-dose clobazam to an established cenobamate ...
Gonzalo Miranda
core   +1 more source

Budget impact analysis of cenobamate for epilepsy patients with drug-resistant focal onset seizures in the Netherlands

ObjectiveThe objective of this study was to explore the financial consequences of adopting cenobamate as a treatment alternative in epilepsy patients with drug-resistant focal onset seizures (FOS) from a societal perspective in the Netherlands.MethodsA ...
Rijkers, Kim, Evers, Silvia; id_orcid, Lazeron, Richard, Klarenbeek, Pim, Laskier-Owens, Vicki, Hiligsmann, Mickael, Rouhl, Rob, Li, Nannan, Majoie, Marian, Gubler, Felix   +9 more
core   +1 more source

To Delay or Not to Delay: The Role Cenobamate Plays in the Presurgical Evaluation. [PDF]

Epilepsy Curr
Widdess-Walsh P.
europepmc   +1 more source

Cenobamate add-on therapy for drug-resistant focal epilepsy

Background: Although most people with epilepsy achieve complete seizure cessation, approximately one-third of those with the condition continue experiencing seizures despite the use of antiseizure medications (ASMs) given as monotherapy or polytherapy ...
Brigo, Francesco, Lattanzi, Simona
core   +1 more source

New-Generation Antiseizure Medications: Who Takes the Lead in the Real World? [PDF]

Epilepsy Curr
Taraschenko O.
europepmc   +1 more source

A New Antiseizure Medication: Cenobamate

Epilia: Epilepsy and Community, 2023
openaire   +1 more source