Differential Gene Expression in Human Hippocampus With Aging
Aging Cell, Volume 25, Issue 4, April 2026.2 complementary analysis from a transcriptome study in human hippocampal samples of different ages revealed a set of genes differentially expressed in aged individuals linked to inflammation and immune system pathways, DNA repair (RAD23) or neural activity.
Ander Saenz‐Antoñanzas +9 more
wiley +1 more source
Aging Cell, Volume 25, Issue 4, April 2026.A 14‐protein extracellular matrix aging clock derived from circulating matrisome proteins predicts chronological and biological age across cohorts and biofluids, distinguishes health from disease, and is modulated by rejuvenation interventions in mice, enabling the nomination of potential ECM targets for drug discovery to promote healthy aging ...
Loet Coenen +4 more
wiley +1 more source
Centenarians and diet: what they eat in the Western part of Sicily. [PDF]
, 2012 This paper pays attention to the modifiable lifestyle factors such as diet and nutrition that might influence life extension and successful ageing. Previous data reported that in Sicily, the biggest Mediterranean island, there are some places where there
CARUSO, Calogero +2 more
core +3 more sources
Overlap of Frailty, Comorbidity, Disability, and Poor Self-Rated Health in Community-Dwelling Near-Centenarians and Centenarians [PDF]
, 2016 postprin
Charlson +9 more
core +1 more source
Depression Moderates the Frailty–Subjective Health Link among Chinese Near Centenarians and Centenarians [PDF]
, 2016 published_or_final_versio
Cheung, KSL +3 more
core +1 more source
The Advocate E-Newsletter August 3, 2015 [PDF]
, 2015 Governor signs Senate File 505 into law. The section directly impacting the OSLTCO remains in place resulting in $1,2762783 appropriation for the program. Other highlights are included.
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Beyond the Kannisto-Thatcher Database on Old Age Mortality: an assessment of data quality at advanced ages [PDF]
The old age population in developed countries has been increasing remarkably, yet internationally comparable high quality data on oldest-old mortality remain relatively scarce.
Dmitri A. Jdanov +4 more
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Life extension attitudes and the wish to become a centenarian [PDF]
, 2013 Mestrado em GerontologiaIntrodução: Com o avanço galopante da biologia e o aumento contínuo da esperança média de vida torna-se imperativo analisar as atitudes das pessoas em relação à extensão da vida humana e como estas se relacionam com as atitudes
Garrido, Ana Sofia Martins Ferreira Canedo
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The number of centenarians in Brazil: Indirect estimates based on death certificates [PDF]
The Brazilian population is rapidly aging. As a result, the number of centenarians has grown steadily, about 77 per cent between 1991 and 2000. Although expected, the increasing number of centenarians may be exaggerated by data quality issues. We compare
Cassio M. Turra +1 more
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Longevity Genes: From Primitive Organisms to Humans [PDF]
, 2002 A variety of lines of evidence indicate that aging and longevity are subject to genetic regulation, but until fairly recently the identity of these genes was unknown. This has changed dramatically over the last ten years.
Huber Warner
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