Results 71 to 80 of about 10,375 (215)
Sex hormones and physical function among the Chinese oldest-old and centenarian women
Journal of Translational Medicine, 2022 Background Physical independence is crucial for overall health in the elderly individuals. The life expectancy of women has been shown to be higher than that of men, which is also known as the “male–female health-survival paradox”.
Qiao Zhu +7 more
doaj +1 more source
Journal of Clinical Nursing, Volume 35, Issue 5, Page 2510-2516, May 2026.ABSTRACT Aims The concept of healthy or successful ageing dates back to the 1960s, where its goal is more realistic in today's ageing society as a result of effective interventions to control and reduce disability and health risks. The aim of this paper is to outline the importance of defining ageing, the semantics and indicators used, and to identify ...
C. Donnellan
wiley +1 more source
Whole genome sequences of a male and female supercentenarian, ages greater than 114 years
Frontiers in Genetics, 2012 Supercentenarians (age 110+ years old) generally delay or escape age-related diseases and disability well beyond the age one hundred and this exceptional survival is likely to be influenced by a genetic predisposition that includes both common and rare ...
Paola eSebastiani +12 more
doaj +1 more source
Strikingly higher frequency in centenarians and twins of mtDNA mutation causing remodeling of replication origin in leukocytes [PDF]
, 2003 The presence of a genetic component in longevity is well known. Here, the association of a mtDNA mutation with a prolonged life span in humans was investigated.
Asin-Cayuela, Jordi +9 more
core
Does the longevity of one or both parents influence the health status of their offspring? [PDF]
, 2013 According to the findings of some recent studies, the centenarians' offspring appear to represent a promising model for research on longevity and healthy aging. This study compares the health status and the functional status of three groups of subjects:
Bonafede, E +13 more
core +1 more source
Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.Abstract INTRODUCTION Aging is the strongest risk factor for Alzheimer's disease (AD) characterized by amyloid‐β (Aβ) plaques and tau tangles in the brain. We aim to compare biological aging‐related biomarkers among AD, non‐neurodegenerative control (NDC) and non‐AD neurodegenerative (Non‐AD) individuals to evaluate their clinical utility.
Bryan Ng +7 more
wiley +1 more source
Paraoxonase Activity and Genotype Predispose to Successful Aging [PDF]
, 2017 The paraoxonase 1 codon 192 R allele has been previously reported to have a role in successful aging. The relationship between PON1 genotypes, enzymatic activity, and mass concentration was evaluated in a group of 229 participants from 22 to 104 years of
Boemi, Massimo +9 more
core
Interior metric and ray-tracing map in the firework black-to-white hole transition [PDF]
, 2018 The possibility that a black hole could tunnel into a white hole has recently received attention. Here we present a metric that improves the 'firework' metric: it describes the entire process and solves the Einstein equations everywhere except on a small
Martin-Dussaud, Pierre, Rovelli, Carlo
core +3 more sources
Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.Abstract INTRODUCTION Parental history of dementia is associated with increased dementia risk. We investigated whether having a parent with dementia is associated with increased peripheral inflammation in middle‐aged adults. METHODS Participants were from the Offspring Study (n = 1204).
Edric D. Winford +8 more
wiley +1 more source
mSystems, 2019 Sardinia, Italy, has a high prevalence of residents who live more than 100 years. The reasons for longevity in this isolated region are currently unknown. Gut microbiota may hold a clue.
Lu Wu +5 more
doaj +1 more source