Results 51 to 60 of about 5,271 (209)

Whole genome sequences of a male and female supercentenarian, ages greater than 114 years

Frontiers in Genetics, 2012
Supercentenarians (age 110+ years old) generally delay or escape age-related diseases and disability well beyond the age one hundred and this exceptional survival is likely to be influenced by a genetic predisposition that includes both common and rare ...
Paola eSebastiani, Alberto eRiva, Monty eMontano, Phillip ePham, Ali eTorkamani, Eugene eScherba, Gary eBenson, Jacqueline N Milton, Clinton T Baldwin, Stacy eAndersen, Nicholas J Schork, Martin H Steinberg, Thomas T Perls   +12 more
doaj   +1 more source

Body donor programs in Australia and New Zealand: Current status and future opportunities

Anatomical Sciences Education, Volume 18, Issue 3, Page 301-328, March 2025.
Abstract Body donation is critical to anatomy study in Australia and New Zealand. Annually, more than 10,000 students, anatomists, researchers, and clinicians access tissue donated by local consented donors through university‐based body donation programs. However, little research has been published about their operations.
Rebekah A. Jenkin, Kevin A. Keay
wiley   +1 more source

Association Characteristics and Potential Mechanisms of Aging, Gut Microbiota, and Hearing Loss

Integrative Zoology, EarlyView.
The study found that aging leads to unchanged gut microbiota alpha diversity but an increase in Bacteroidetes and a decrease in Firmicutes at the phylum level, with specific genera, species, and functional pathways co‐associated with aging and hearing loss. Through constructing a microbe‐metabolite network, it revealed the mechanism by which protective
Cheng Cheng, Lu Wang, Runhan Li, Wenkai Lai, Chongkui Sun, Jianguo Cui, Bicheng Zhu, Jiang Zhang   +7 more
wiley   +1 more source

A Cross-Sectional Study of Compositional and Functional Profiles of Gut Microbiota in Sardinian Centenarians

mSystems, 2019
Sardinia, Italy, has a high prevalence of residents who live more than 100 years. The reasons for longevity in this isolated region are currently unknown. Gut microbiota may hold a clue.
Lu Wu, Tiansheng Zeng, Angelo Zinellu, Salvatore Rubino, David J. Kelvin, Ciriaco Carru   +5 more
doaj   +1 more source

Analysis of Quantitative Relationship between Dietary Characteristics and Health Indicators of Long-lived Population by Random Forest Regression Algorithm

Shipin gongye ke-ji, 2022
To explore the potential quantitative relationship between dietary characteristics and physical health indicators of the long-lived population in Guangxi, the longevous in Guangxi (Fengshan County, Donglan County, Shanglin County, Dahua County, and Cenxi
Jinke MA, Yao SONG, Kunchen HAN, Wenjun ZHU, Xiaohan YU, Qinren ZHANG, Xiyu ZHANG, Quanyang LI   +7 more
doaj   +1 more source

Index of crown vigour in centenarian oaks

, 2016
This file contain data on ICV of centenarian oaks inside and outside ...
Jose m. Fedriani (790527), Luis V. García (677772), Luis V. García3, María E. Sánchez4, Juan Calderón1, and Cristina Ramo1 (2581699)   +2 more
core   +1 more source

Adipokines and Aging: Findings From Centenarians and the Very Old

Frontiers in Endocrinology, 2019
Adipose tissue, which was once considered as a simple energy storage depot, is now recognized as an active endocrine organ that regulates the whole-body energy homeostasis by secreting hundreds of bioactive substances termed adipokines.
Yasumichi Arai, Kei Kamide, Nobuyoshi Hirose   +2 more
doaj   +1 more source

GNB3, eNOS, and mitochondrial DNA polymorphisms correlate to natural longevity in a Xinjiang Uygur population. [PDF]

PLoS ONE, 2013
BACKGROUND: In centenarian populations, application of the positive biology approach (examination of positive phenotypes in aging) has revealed that mitochondrial DNA (mtDNA) mutation accumulation may be linked to human longevity; however, the role of ...
Muyesai Nijiati, Abulajiang Saidaming, Jun Qiao, Zuheng Cheng, Changchun Qiu, Yujing Sun   +5 more
doaj   +1 more source

Habitual fasting duration and accelerated multimorbidity in older adults

Journal of Internal Medicine, EarlyView.
Abstract Background Prolonged fasting has been linked to metabolic benefits in younger adults, but its effects on chronic diseases in older populations remain unclear. Objective To examine the association between habitual fasting duration and 15‐year chronic disease accumulation in older adults, overall, within organ systems, and between age groups ...
Luis Kalmbach, David Abbad‐Gomez, Giorgi Beridze, Fernando Rodríguez‐Artalejo, Davide Liborio Vetrano, Amaia Calderón‐Larrañaga, Adrián Carballo‐Casla   +6 more
wiley   +1 more source

A demographic perspective on longevity and healthspan: Rethinking population ageing through a positive and prospective lens

Journal of Internal Medicine, EarlyView.
Abstract Population ageing is portrayed as a threat to the sustainability of health and welfare systems. This narrative—grounded in static chronological definitions of old age—risks overstating the burden of increasing longevity while overlooking changes in survival, health and population composition. In this article, we adopt a demographic perspective
Daniele Vignoli, Cosmo Strozza, Agar Brugiavini, Davide Liborio Vetrano, Amaia Calderón‐Larrañaga, Serhiy Dekhtyar, Pietro Grassi, Chiara Seghieri   +7 more
wiley   +1 more source