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North Dakota Centenarian Study Interviews, 1999 [PDF]

open access: yes, 2011
The North Dakota Centenarian Study Interviews consists of seven video interviews, done as a grant-funded project administered by Dr. Greg Sanders of the NDSU Department of Child Development and Family Science, and Candace Philbrick conducted the actual ...
North Dakota Centenarian Study Interviews
core  

Decline in blood hemoglobin concentrations is associated with familial longevity [PDF]

open access: yesArchives of Biological Sciences, 2016
Hemoglobin(HGB)in the blood carries oxygen from the lungs to other organs to produce energy. Calorie restriction has been shown to slow aging and extend lifespan.
He Yong-Han   +12 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Centenarian [PDF]

open access: yes, 2018
A centenarian is an individual who has survived to the age of 100, approximately 20 years longer than the average life expectancy. The number of centenarians in the United States has increased and will continue to increase.
Martin, Peter, Baek, Yousun
core  

Sicilian centenarian offspring are more resistant to immune ageing

open access: yes, 2018
Background: Immunosenescence constitutes a major indirect cause of morbidity and mortality in the elderly. Previous analysis of immune signatures in a cohort of centenarian offspring showed an intermediate immunophenotype between age-matched and younger ...
Bulati, Matteo   +15 more
core   +1 more source

Associations between lipid profiles and late‐life cognitive impairment among oldest‐old and centenarian adults

open access: yesMedComm, 2023
Dyslipidemia and cognitive impairment are common among old adults and the occurrence of them rises exponentially with increasing age. Evidences of the relationships between serum lipids and cognitive impairment are inconsistent or equivocal among older ...
Yujian Chen   +7 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Single‐Cell Transcriptomics Reveals Longevity Immune Remodeling Features Shared by Centenarians and Their Offspring

open access: yesAdvanced Science, 2022
Centenarians, who show mild infections and low incidence of tumors, are the optimal model to investigate healthy aging. However, longevity related immune characteristics has not been fully revealed largely due to lack of appropriate controls.
Chen Dong   +25 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

ICV of non-centenarian oaks

open access: yes, 2016
This file contains data concerning ICV of non-centenarian ...
José M. Fedriani1,2, Luis V. García3, María E. Sánchez4, Juan Calderón1, and Cristina Ramo1 (2581729)
core   +1 more source

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