Results 31 to 40 of about 3,476 (178)

The ‘autoimmunome’ of centenarians

Journal of Translational Autoimmunity
To identify signature proteins potentially linked to resistance to autoimmunity in the blood of centenarians.We conducted in silico data mining of previously published proteomic results using the Search Tool for the Retrieval of Interacting Genes/Proteins (STRING) and PHENOPEDIA databases.Sixteen autoimmune disease-related proteins were identified ...
Carrera Bastos, Pedro, Plaza Florido, Abel, Santos Lozano, Alejandro, Borba, Vânia, Rodríguez Romo, Gabriel, García Chico, Celia, Lista, Simone, Saco Ledo, Gonzalo, Emanuele, Enzo, Shoenfeld, Yehuda, Lucia, Alejandro   +10 more
openaire   +3 more sources

Epidemiological characteristics of centenarian deaths in China during 2013–2020: A trend and subnational analysis

Chinese Medical Journal
. Background:. Studies that comprehensively address the characteristics of centenarian deaths are rare. The present study aimed to depict the characteristics of centenarian deaths in China and their changing trends. Methods:.
Fan Mao, Weiwei Zhang, Peng Yin, Lijun Wang, Jinling You, Jiangmei Liu, Yunning Liu, Maigeng Zhou, Jing Ni   +8 more
doaj   +1 more source

Higher Normal Levels of Triglyceride and Low and High-Density Lipoprotein Cholesterol Might Have a Protective Effect Against Activities of Daily Living Disability Within Chinese Female Centenarians: A Cross-Sectional, Complete Sample Study

Clinical Interventions in Aging, 2020
Shengshu Wang,1 Miao Liu,1,2 Shanshan Yang,1 Jianhua Wang,1,2 Wangping Jia,1 Wenzhe Cao,1 Ke Han,1 Yao He1,2 1Institute of Geriatrics, The 2nd Medical Center, Beijing Key Laboratory of Aging and Geriatrics, National Clinical Research Center for ...
Wang S, Liu M, Yang S, Wang J, Jia W, Cao W, Han K, He Y   +7 more
doaj  

Dietary patterns influencing the human colonic microbiota from infancy to centenarian age: a narrative review

Frontiers in Nutrition
Our dietary choices not only affect our body but also shape the microbial community inhabiting our large intestine. The colonic microbiota strongly influences our physiology, playing a crucial role in both disease prevention and development.
Vitor Geniselli da Silva, Vitor Geniselli da Silva, Nicole Clémence Roy, Nicole Clémence Roy, Nicole Clémence Roy, Nick William Smith, Clare Wall, Clare Wall, Jane Adair Mullaney, Jane Adair Mullaney, Jane Adair Mullaney, Warren Charles McNabb, Warren Charles McNabb   +12 more
doaj   +1 more source

Decline in blood hemoglobin concentrations is associated with familial longevity [PDF]

Archives of Biological Sciences, 2016
Hemoglobin(HGB)in the blood carries oxygen from the lungs to other organs to produce energy. Calorie restriction has been shown to slow aging and extend lifespan.
He Yong-Han, Pu Shao-Yan, Li Wen, Chen Xiao-Qiong, Xiao Fu-Hui, Yan Dong-Jing, Liu Yao-Wen, Lin Rong, Liao Xiao-Ping, Yang Xing-Li, Ge Ming-Xia, Cai Wang-Wei, Kong Qing-Peng   +12 more
doaj   +1 more source

A case of a centenarian in whom complete atrioventricular block that had persisted for 3 months disappeared after treatment for heart failure

Journal of Hospital General Medicine, 2023
A 104-year-old man was admitted to our hospital with a complaint of dyspnea. He was diagnosed as having congestive heart failure associated with complete atrioventricular (AV) block and had a heart rate (HR) of 40 beats/min.
Tetsuya Kawabe, Kazumi Kawabe, Yoshiaki Minakata   +2 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Associations between lipid profiles and late‐life cognitive impairment among oldest‐old and centenarian adults

MedComm, 2023
Dyslipidemia and cognitive impairment are common among old adults and the occurrence of them rises exponentially with increasing age. Evidences of the relationships between serum lipids and cognitive impairment are inconsistent or equivocal among older ...
Yujian Chen, Kaidi Yang, Ya Huang, Xuejiao Wang, Yali Zhao, Ping Ping, Shasha Guan, Shihui Fu   +7 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Single‐Cell Transcriptomics Reveals Longevity Immune Remodeling Features Shared by Centenarians and Their Offspring

Advanced Science, 2022
Centenarians, who show mild infections and low incidence of tumors, are the optimal model to investigate healthy aging. However, longevity related immune characteristics has not been fully revealed largely due to lack of appropriate controls.
Chen Dong, Ya‐ru Miao, Rui Zhao, Mei Yang, An‐yuan Guo, Zhong‐hui Xue, Teng Li, Qiong Zhang, Yanfeng Bao, Chen Shen, Chi Sun, Ying Yang, Xi‐xi Gu, Yi Jin, Rong Li, Min Xu, Jia‐xin Guo, Zhi‐ying Zong, Wei Zhou, Mei He, Dan‐ni Wang, Jian‐you Su, Xiao‐ming Zhang, Xu‐hui Zeng, Jian‐lin Gao, Zhi‐feng Gu   +25 more
doaj   +1 more source