Results 21 to 30 of about 10,375 (215)

Associations between lipid profiles and late‐life cognitive impairment among oldest‐old and centenarian adults

open access: yesMedComm, 2023
Dyslipidemia and cognitive impairment are common among old adults and the occurrence of them rises exponentially with increasing age. Evidences of the relationships between serum lipids and cognitive impairment are inconsistent or equivocal among older ...
Yujian Chen   +7 more
doaj   +1 more source

Single‐Cell Transcriptomics Reveals Longevity Immune Remodeling Features Shared by Centenarians and Their Offspring

open access: yesAdvanced Science, 2022
Centenarians, who show mild infections and low incidence of tumors, are the optimal model to investigate healthy aging. However, longevity related immune characteristics has not been fully revealed largely due to lack of appropriate controls.
Chen Dong   +25 more
doaj   +1 more source

Centenarian longevity had inverse relationships with nutritional status and abdominal obesity and positive relationships with sex hormones and bone turnover in the oldest females

open access: yesJournal of Translational Medicine, 2021
Objective The number of older people is estimated to increase from 524 million in 2010 to 1.5 billion in 2050. The factors and models of human longevity and successful aging are questions that have intrigued individuals for thousands of years.
Shihui Fu   +6 more
doaj   +1 more source

Effects of age, period, and cohort on the prevalence of frailty in Chinese older adults from 2002 to 2014

open access: yesFrontiers in Public Health, 2022
BackgroundCurrently, longitudinal studies on frailty are in an early stage, particularly in low- and middle-income countries. Only one study was conducted in Hong Kong to examine age-period-cohort effects on the prevalence of frailty among Chinese older ...
Siying Li   +5 more
doaj   +1 more source

B Cells Compartment in Centenarian Offspring and Old People [PDF]

open access: yes, 2010
Immunosenescence is considered a major contributory factor to the increased frequency of morbidity and mortality among elderly. On the other hand centenarians are considered the best example of successful ageing.
BUFFA, Silvio   +7 more
core   +1 more source

Immunosenescence, aging and successful aging

open access: yesFrontiers in Immunology, 2022
Aging induces a series of immune related changes, which is called immunosenescence, playing important roles in many age-related diseases, especially neurodegenerative diseases, tumors, cardiovascular diseases, autoimmune diseases and coronavirus disease ...
Yunan Wang   +4 more
doaj   +1 more source

The light and shadow of senescence and inflammation in cardiovascular pathology and regenerative medicine [PDF]

open access: yes, 2017
Recent epidemiologic studies evidence a dramatic increase of cardiovascular diseases, especially associated with the aging of the world population. During aging, the progressive impairment of the cardiovascular functions results from the compromised ...
Cavarretta, Elena   +9 more
core   +4 more sources

Nutritional Management in a 101-Year-Old Woman with Physical Inactivity and General Weakness: A Case Report

open access: yesGeriatrics, 2023
Japan has the world’s highest life longevity, and centenarian patients are no longer rare. However, sufficient information related to centenarians is not available. Herein, we report the case of a 101-year-old centenarian woman who recovered from extreme
Ryoko Mineyama   +4 more
doaj   +1 more source

Characteristics of centenarian studies and variables related to longevity: A narrative review

open access: yesJournal of the Indian Academy of Geriatrics, 2023
Studying centenarians requires a “positive biology” approach, where rather than focusing on disease, the research aims to understand the causes of positive phenotypes and explain biological mechanisms of health and longevity.
Shyh Poh Teo
doaj   +1 more source

Cognitive Health of Nonagenarians in Southern Italy: A Descriptive Analysis from a Cross-Sectional, Home-Based Pilot Study of Exceptional Longevity (Cilento Initiative on Aging Outcomes Or CIAO). [PDF]

open access: yes, 2020
Background: Nonagenarians and centenarians (NCs) are an extremely fragile population, particularly in regard to their physical and cognitive function.
Antonini, Paola   +8 more
core   +1 more source

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