Results 1 to 10 of about 3,476 (178)

Case Report: endoscopic microvascular decompression for trigeminal neuralgia in a centenarian: a landmark case with 5-year follow-up [PDF]

open access: yesFrontiers in Surgery
BackgroundEndoscopic Microvascular Decompression (E-MVD) is a well-established effective treatment option for trigeminal neuralgia (TN). However, its application in ultra-elderly patients, particularly centenarians, has never been documented.Case ...
Deng Yao
exaly   +4 more sources

The ‘Health Collapse Spiral’: A 35‐Month Longitudinal Case Study of Physiological Reserve Depletion in a Centenarian Following COVID‐19 [PDF]

open access: yesClinical Case Reports
This 35‐month case report documents irreversible physiological reserve depletion in a centenarian multimorbid man after COVID‐19. Prior to infection, he maintained precarious homeostasis for 17 years despite severe frailty (CFS 7), with stable CKD stage ...
Shan Xu   +5 more
doaj   +2 more sources

Adherence to various dietary quality indices of centenarian offspring in the New England Centenarian Study [PDF]

open access: yesThe Journal of Nutrition, Health and Aging
Background: Many centenarian offspring (CO) show survival and health advantages compared to population controls, yet little is known about their dietary patterns. The New England Centenarian Study (NECS) offers an opportunity to characterize diet quality
Erfei Zhao   +10 more
doaj   +2 more sources

Edentulousness and the Likelihood of Becoming a Centenarian: Longitudinal Observational Study [PDF]

open access: yesJMIR Aging
BackgroundIn recent decades, the global life expectancy has risen notably to approximately 73.5 years worldwide, coinciding with a rapid growth in the older adult population, which presents a significant public health challenge in promoting healthy aging
Xindi Wei   +6 more
doaj   +2 more sources

Nutrition and longevity – diet in centenarians [PDF]

open access: yesJournal of Translational Medicine
Background Nutrition plays a central role in the biological mechanisms that shape aging, health span, and longevity. Micronutrients—including vitamins, trace elements, and polyphenols—support genomic stability, mitochondrial integrity, and antioxidant ...
Evelyn Frias-Toral   +10 more
doaj   +2 more sources

Mutant Single Nucleotide Polymorphism rs189037 in Ataxia-Telangiectasia Mutated Gene Is Significantly Associated With Ventricular Wall Thickness and Human Lifespan

open access: yesFrontiers in Cardiovascular Medicine, 2021
In the current study, we aimed to determine the association of single nucleotide polymorphism rs189037 in ataxia-telangiectasia mutated (ATM) gene with cardiac structure and human longevity. Based on the China Hainan Centenarian Cohort Study performed in
Shihui Fu   +10 more
doaj   +1 more source

A case of successful thoracic endovascular aneurysm repair in a 106-year-old female

open access: yesIndian Journal of Vascular and Endovascular Surgery, 2021
As the population ages, the average age of patients is expected to rise. Here, we describe a successful case of thoracic endovascular aneurysm repair (TEVAR) performed in a 106-year-old female.
Kanako Kobayashi   +3 more
doaj   +1 more source

Female Fertility Has a Negative Relationship With Longevity in Chinese Oldest-Old Population: A Cross-Sectional Study

open access: yesFrontiers in Endocrinology, 2021
BackgroundDespite research efforts in this field for more than a century, the relationship between female fertility and longevity is unclear. This study was designed to investigate this relationship in Chinese oldest-old population.MethodsThe China ...
Qiao Zhu   +6 more
doaj   +1 more source

Centenarian longevity had inverse relationships with nutritional status and abdominal obesity and positive relationships with sex hormones and bone turnover in the oldest females

open access: yesJournal of Translational Medicine, 2021
Objective The number of older people is estimated to increase from 524 million in 2010 to 1.5 billion in 2050. The factors and models of human longevity and successful aging are questions that have intrigued individuals for thousands of years.
Shihui Fu   +6 more
doaj   +1 more source

Effects of age, period, and cohort on the prevalence of frailty in Chinese older adults from 2002 to 2014

open access: yesFrontiers in Public Health, 2022
BackgroundCurrently, longitudinal studies on frailty are in an early stage, particularly in low- and middle-income countries. Only one study was conducted in Hong Kong to examine age-period-cohort effects on the prevalence of frailty among Chinese older ...
Siying Li   +5 more
doaj   +1 more source

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