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Centenarian clocks: epigenetic clocks for validating claims of exceptional longevity [PDF]
Claims surrounding exceptional longevity are sometimes disputed or dismissed for lack of credible evidence. Here, we present three DNA methylation-based age estimators (epigenetic clocks) for verifying age claims of centenarians.
Steve Horvath
exaly +4 more sources
Centenarian Offspring: Start Healthier and Stay Healthier
OBJECTIVES: To assess the relative incidence of age-related diseases in a group of centenarian offspring who have thus far been considered to be predisposed to healthy aging. DESIGN: Longitudinal study. SETTING: Nationwide sample.
Stacy L Andersen, Thomas Perls
exaly +2 more sources
Centenarian athletes: Examples of ultimate human performance?
International audienceBackground: some centenarians are engaged in regular physical activity and sometimes in sporting events.Objective: we aimed to identify world records of centenarian athletes in several sports and determine which represented the best
Thomas Cattagni, Paul Stapley
exaly +2 more sources
Objective: This study examined the association of several social and environmental factors on the likelihood of reaching centenarian age for older adults in Washington State.
Dedra Buchwald +2 more
exaly +2 more sources
A centenarian-only approach for assessing gene–gene interaction in human longevity
In this study, we introduce a centenarian-only approach to the assessment of gene-gene interaction that contributes to human longevity. This approach corresponds to the non-traditional case-only method in the genetic study of gene and disease ...
Claudio Franceschi +2 more
exaly +2 more sources
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2020
As the oldest continent of the word, Europe presently faces an unprecedented demographic scenario. The number of individuals reaching very advanced ages is growing significantly, and within this age group a very particular one: centenarians. Living up to be 100 years of age, although reachable to only a few of us, is likely to become more common, and ...
Teixeira, Laetitia +3 more
openaire +2 more sources
As the oldest continent of the word, Europe presently faces an unprecedented demographic scenario. The number of individuals reaching very advanced ages is growing significantly, and within this age group a very particular one: centenarians. Living up to be 100 years of age, although reachable to only a few of us, is likely to become more common, and ...
Teixeira, Laetitia +3 more
openaire +2 more sources
Pacing and Clinical Electrophysiology, 1994
Background: Many studies have shown an increase in the prevalence of arrhythmias with advancing age. However, little is known about arrhythmias in centenarians. Method and Results: Thirty‐two Japanese centenarians aged 100–106 years (14 males, 18 females) were studied. All of them had 12‐lead EGGs, and 22 also had 24‐hour ambulatory monitoring.
Y, Wakida +7 more
openaire +2 more sources
Background: Many studies have shown an increase in the prevalence of arrhythmias with advancing age. However, little is known about arrhythmias in centenarians. Method and Results: Thirty‐two Japanese centenarians aged 100–106 years (14 males, 18 females) were studied. All of them had 12‐lead EGGs, and 22 also had 24‐hour ambulatory monitoring.
Y, Wakida +7 more
openaire +2 more sources
Electroencephalography and Clinical Neurophysiology, 1976
1. The EEGs of ten centenarians were described. 2. In most healthy centenarians, posterior dominant rhythms are within the lower part of the alpha range (average 8.62 c/sec). 3. Although slowing of the posterior dominant rhythm at age 100 is greater than in younger groups, there is no evidence in this study of a progressive decrease in frequency during
O, Hubbard, D, Sunde, E S, Goldensohn
openaire +2 more sources
1. The EEGs of ten centenarians were described. 2. In most healthy centenarians, posterior dominant rhythms are within the lower part of the alpha range (average 8.62 c/sec). 3. Although slowing of the posterior dominant rhythm at age 100 is greater than in younger groups, there is no evidence in this study of a progressive decrease in frequency during
O, Hubbard, D, Sunde, E S, Goldensohn
openaire +2 more sources

