Results 51 to 60 of about 2,878,986 (275)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Chiellini Hamiltonian Lienard differential systems
Electronic Journal of Differential Equations, 2019 We characterize the centers of the Chiellini Hamiltonian Lienard second-order differential equations $x'=y$, $y'=-f(x) y -g(x)$ where $g(x)=f(x) (k - \alpha (1 +\alpha) \int f(x) dx )$ with $\alpha, k \in \mathbb{R}$.
Jaume Gine, Jaume Llibre, Claudia Valls
doaj
Jurnal Bimbingan dan Konseling Terapan, 2019 The application of learning and the use of the proper learning model really need to be considered in order to help find out students' understanding of what is conveyed by the teacher. Problem Based Learning is a learning model that focuses on students or
Siti Seituni
doaj +1 more source
On the center-focus problem for the equation $\frac{dy}{dx} + \sum_{i=1}^n a_i(x) y^i = 0, 0\leq x \leq 1$ where $a_i$ are polynomials [PDF]
Annales Henri Lebesgue, 2020 We study irreducible components of the set of polynomial plane differential systems with a center, which can be seen as a modern formulation of the classical center-focus problem. The emphasis is given on the interrelation between the geometry of the center set and the Picard–lefschetz theory of the bifurcation (or Poincaré–Pontryagin–Melnikov ...
openaire +3 more sources
Effect of aspect ratio on transverse diffusive broadening: A lattice Boltzmann study
, 2009 We study scaling laws characterizing the inter-diffusive zone between two miscible fluids flowing side by side in a Y-shape laminar micromixer using the lattice Boltzmann method.
Ayodele, S. G., Raabe, D., varnik, F.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The radical of the focal values ideal of the complex Kukles system
Журнал Белорусского государственного университета: Математика, информатика, 2018 In the article it is considered the center-focus problem for complex Kukles system x = y, y = -x + Ax2 + 3Bxy + Cy2 + Kx3 + 3Lx2y + Mxy2 + Ny3. The problem is solved by the new method, obtained by A. P.
Anton P. Sadovskii +2 more
doaj
Monodromy problem and Tangential center-focus problem for product of generic lines in $\mathbb{P}^2$
, 2022 We consider the rational map $F$ defined by the quotient of products of lines in general position and we study the monodromy problem and tangential center-focus problem for the fibration associated with $F$. Thus, we study the submodule of the 1-homology group of a regular fiber of $F$ generated by the orbit of the monodromy action on a vanishing cycle.
openaire +2 more sources
Do we understand the incompressibility of neutron-rich matter?
, 2009 The ``breathing mode'' of neutron-rich nuclei is our window into the incompressibility of neutron-rich matter. After much confusion on the interpretation of the experimental data, consistency was finally reached between different models that predicted ...
Bohr A +6 more
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source