Results 81 to 90 of about 2,878,986 (275)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

The problem of general center-focus and bifurcation of limit cycles for a planar system of nine degrees

Journal of Computational and Applied Mathematics, 2009
This paper considers the system \[ \begin{aligned} {dx\over d\tau} &=-(x\delta+ y)(x^2+ y^2)^4- P_8(x, y),\\ {dy\over d\tau} &=(x- y\delta)(x^2+ y^2)^4+ Q_8(x,y),\end{aligned}\tag{1} \] where \(P_8\), \(Q_8\) are a polynomial of degree \(8\). This system has three singular points of center-focus type \((-{1\over 2}, 0)\), \((-{1\over 2},{1\over 2})\), \
Du, Chaoxiong, Liu, Yirong
openaire   +2 more sources

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Around the Poincaré center-focus problem

, 2018
Multe modele matematice folosesc sisteme de ecuatii diferentiale si aplica teoria calitativa a ecuatiilor diferentiale, elaborata de Poincare si Liapuno . Una din probleme ce persista ^n studiul acestor sisteme consta ^n determinarea conditiilor care asigura ca punctul singular este un centru Problema Centrului si Focarului.
Cioban, M.M., Choban, M.M.
openaire   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Scene Reconstruction from Multiple Images with Single Centre of Projection

Arid Zone Journal of Engineering, Technology and Environment, 2018
One problem which has remained deeply rooted in multi-view geometry is the reconstruction of a three-dimensional (3D) scene starting with multiple two-dimensional (2D) representations of different parts of the same scene. In this paper, the main focus is
A. I. Audu, A. H. Sadka
doaj  

Optimizing Placement and Scheduling for VNF by a Multi-objective Optimization Genetic Algorithm

International Journal of Computational Intelligence Systems
Virtual network functions (VNFs) have gradually replaced the implementation of traditional network functions. Through efficient placement, the VNF placement technology strives to operate VNFs consistently to the greatest extent possible within restricted
Phan Duc Thien, Fan Wu, Mahmoud Bekhit, Ahmed Fathalla, Ahmad Salah   +4 more
doaj   +1 more source