Results 151 to 160 of about 20,208,357 (389)

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Clinton Maintains NH Lead 11/20/2007 [PDF]

open access: yes, 2007
Hillary Clinton continues to lead in the New Hampshire Democratic primary race. However, almost half of Democratic voters say they have yet to make their final choice.
Survey Center, UNH
core   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

Bush Approval Ratings Steady, NH Split on Iraq and Social Security Reform 2/14/2005 [PDF]

open access: yes, 2005
Despite an election victory, an improving economy, and a successful election in Iraq, President Bush’s job approval ratings in New Hampshire have remained unchanged.
Survey Center, UNH
core   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Where Are You Going, Humanity?

open access: yesEIRP Proceedings, 2015
According to evolutionary spiral, every point is a center and any center becomes a point... No trace of a Centre, but just a too small Point… Or, more down to earth (with a mundane speech) , we speak of greatness and decay of a society, a state, a ...
Constantin Frosin
doaj  

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy