Results 291 to 300 of about 20,872,194 (388)

HIV Status and COVID-19 Treatment Disparities in the US National Clinical Cohort Collaborative. [PDF]

Open Forum Infect Dis
Essam Nkodo EN, Maheria P, Hurwitz E, Anzalone AJ, Li D, Islam JY, Sun J, Varley CD, Butzin-Dozier Z, Safo SE, Kirksey K, Hassan SA, Camacho-Rivera M, Patel RC, Fadul N.   +14 more
europepmc   +1 more source

Referee report. For: Effectiveness of 36 hospital learning centers in Thailand: continuation of child patient education, parent attitudes toward child’s illness and service satisfaction [version 2; peer review: 2 approved, 1 not approved]

Banchaun Benjasuwantep
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Survival of Patients with Acute Myeloid Leukemia Relapsing after Allogeneic Hematopoietic Cell Transplantation: A Center for International Blood and Marrow Transplant Research Study

, 2014
Nelli Bejanyan, Daniel J. Weisdorf, Brent R. Logan, Hai-Lin Wang, Steven M. Devine, Marcos de Lima, Donald Bunjes, Mei-Jie Zhang   +7 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Correction: Althenayyan et al. Alternatively Spliced Isoforms of MUC4 and ADAM12 as Biomarkers for Colorectal Cancer Metastasis. J. Pers. Med. 2023, 13, 135. [PDF]

J Pers Med
Althenayyan S, AlMuhanna MH, AlAbdulrahman A, Alghanem B, Alsagaby SA, Alfahed A, Alasiri G, Aziz MA.   +7 more
europepmc   +1 more source

Optimizing Patient-Centered Opioid Tapering with Mindfulness-Oriented Recovery Enhancement

Cooperman, Nina, Garland, Eric L
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Prognosis of Infective Endocarditis According to Clinical Characteristics, Economic Status, and Center Experience. [PDF]

Yonsei Med J
Kim WD, Seo J, Lee S, Kim DY, Kim H, Shim CY, Ha JW, Hong GR, Cho I, Hwang JW.   +9 more
europepmc   +1 more source