Results 31 to 40 of about 7,077,115 (219)

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Limit cycles bifurcated from a center in a three dimensional system

Electronic Journal of Differential Equations, 2016
Based on the pseudo-division algorithm, we introduce a method for computing focal values of a class of 3-dimensional autonomous systems. Using the $\epsilon^1$-order focal values computation, we determine the number of limit cycles bifurcating from ...
Bo Sang, Brigita Fercec, Qin-Long Wang
doaj  

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Analysis of Multi-center Longitudinal Data Using Multilevel Model for Assessing the Relationship between Work Schedule and Body Mass Index Among Staff of Mobarakeh Steel and Polyacryl Companies

مجله اپیدمیولوژی ایران, 2018
Background and Objectives: Shift work could threaten health in the long term. The present research aimed to assess the association between shift work and body mass index (BMI) using the multilevel (hierarchical) model during a particular period of time ...
M Amini, A Kazemnejad, F Zayeri, M Gholami Fesharaki   +3 more
doaj  

On an analogue of Schur's theorem for Leibniz $n$-algebras

Researches in Mathematics
In this paper, we investigate relationships between certain important subalgebras of Leibniz $n$-algebras. In particular, we establish a close connection between the central factor-algebra of a Leibniz $n$-algebra and its derived ideal. As an application,
A.V. Petrov, O.O. Pypka, I.V. Shyshenko
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Linearizability conditions of quasi-cubic systems

Electronic Journal of Qualitative Theory of Differential Equations, 2012
In this paper we study the linearizability problem of the two-dimensional complex quasi-cubic system $\dot{z}=z+(zw)^{d}(a_{30}z^{3}+a_{21}z^{2}w+a_{12}zw^2+a_{03}w^{3}),~\dot{w}=-w-(zw)^{d}(b_{30}w^{3}+b_{21}w^{2}z+b_{12}wz^2+b_{03}z^{3})$, where $z, w,
Wentao Huang, Xingyu Fan, Xingwu Chen
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Positioning Animal Welfare in the One Health Concept through Evaluation of an Animal Welfare Center in Skopje, Macedonia

Frontiers in Veterinary Science, 2018
The Animal Welfare Center (AWC) in Macedonia was established in 2009. The objectives of the center are animal welfare (AW) education, research, raising public awareness of AW, and increasing cooperation between the stakeholders.
Miroslav Radeski, Helen O’Shea, Daniele De Meneghi, Vlatko Ilieski   +3 more
doaj   +1 more source