Results 121 to 130 of about 306,199 (304)

Stability and Hopf Bifurcation Analysis of a Gene Expression Model with Diffusion and Time Delay

Abstract and Applied Analysis, 2014
We consider a model for gene expression with one or two time delays and diffusion. The local stability and delay-induced Hopf bifurcation are investigated.
Yahong Peng, Tonghua Zhang
doaj   +1 more source

Almgren’s center manifold in a simple setting [PDF]

, 2020
Camillo De Lellis
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Nilpotent centers from analytical systems on center manifolds

, 2023
Claudio Pessoa, Lucas Queiroz
openalex   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Periodic Center Manifolds for DDEs in the Light of Suns and Stars

, 2023
Bram Lentjes, Len Spek, Maikel M. Bosschaert, Yuri A. Kuznetsov   +3 more
openalex   +2 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Center manifolds for a class of degenerate evolution equations and existence of small-amplitude kinetic shocks [PDF]

, 2018
Alin Pogan, Kevin Zumbrun
openalex   +1 more source

Radiation Reaction and Center Manifolds

, 1999
We study the effective dynamics of a mechanical particle coupled to a wave field and subject to the slowly varying potential $V(\eps q)$ with $\eps$ small. To lowest order in $\eps$ the motion of the particle is governed by an effective Hamiltonian. In the next order one obtains ``dissipative'' terms which describe the radiation reaction.
Markus, Kunze, Spohn, Herbert
openaire   +2 more sources