Results 101 to 110 of about 64,085 (304)

Flip and Neimark–Sacker Bifurcations in a Coupled Logistic Map System

open access: yesDiscrete Dynamics in Nature and Society, 2020
In this paper, we consider a system of strongly coupled logistic maps involving two parameters. We classify and investigate the stability of its fixed points.
A. Mareno, L. Q. English
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Global Regularization for the n-Center Problem on a Manifold

open access: yes, 2007
We describe a global version of the KS regularization of the n-center problem on a closed 3-dimensional manifold. The regularized con guration manifold turns out to be 4 or 5 dimensional closed manifold depending on whether n is even or odd.
S. V. Bolotin, P. Negrini
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Center manifolds without a phase space

open access: yesTransactions of the American Mathematical Society, 2018
We establish center manifold theorems that allow one to study the bifurcation of small solutions from a trivial state in systems of functional equations posed on the real line. The class of equations includes most importantly nonlinear equations with nonlocal coupling through convolution operators as they arise in the description of spatially extended ...
Faye, Grégory, Scheel, Arnd
openaire   +4 more sources

Computational Scheme of a Center Manifold for Neutral Functional Differential Equations

open access: yes, 2001
This work addresses a computational algorithm of terms of a center manifold for neutral functional differential equations. The Bogdanov–Takens and the Hopf singularities are considered.
Ait Babram, M., Arino, O., Hbid, M.L.
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Bifurcation of Nongeneric Homoclinic Orbit Accompanied by Pitchfork Bifurcation

open access: yesAbstract and Applied Analysis, 2014
The bifurcation of a nongeneric homoclinic orbit (i.e., the orbit comes from the equilibrium along the unstable manifold instead of the center manifold) connecting a nonhyperbolic equilibrium is investigated, and the nonhyperbolic equilibrium undergoes ...
Fengjie Geng, Song Li
doaj   +1 more source

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