Results 81 to 90 of about 4,623,308 (321)
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Entropy, 2014 Information geometry studies the dually flat structure of a manifold, highlighted by the generalized Pythagorean theorem. The present paper studies a class of Bregman divergences called the (ρ,τ)-divergence.
Shun-ichi Amari
doaj +1 more source
Analytic Extension of Riemannian Analytic Manifolds and Local Isometries
Mathematics, 2020 This article deals with a locally given Riemannian analytic manifold. One of the main tasks is to define its regular analytic extension in order to generalize the notion of completeness.
Vladimir A. Popov
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Reduction and normal forms for a delayed reaction–diffusion differential system with B–T singularity
Advances in Difference Equations, 2019 In this paper, we expanded our computation to obtain a simpler and detailed reduction and normal form of a delayed reaction–diffusion differential system with Bogdanov–Takens (B–T) singularity.
Longyue Li, Jianzhi Cao, Yingying Mei
doaj +1 more source
The equivalence between singular point quantities and Liapunov constants on center manifold
, 2012 The algorithm of singular point quantities for an equilibrium of three-dimensional dynamics system is studied. The explicit algebraic equivalent relation between singular point quantities and Liapunov constants on center manifold is rigorously proved. As
Qinlong Wang, Wentao Huang
semanticscholar +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Bogdanov-Takens bifurcation for neutral functional differential equations
Electronic Journal of Differential Equations, 2013 In this article, we consider a class of neutral functional differential equations (NFDEs). First, some feasible assumptions and algorithms are given for the determination of Bogdanov-Takens (B-T) singularity.
Jianzhi Cao, Rong Yuan
doaj
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source