Results 71 to 80 of about 4,623,308 (321)

Running-Induced Fatigue Changes the Structure of Motor Variability in Novice Runners

Biology, 2022
Understanding the effects of fatigue is a central issue in the context of endurance sports. Given the popularity of running, there are numerous novices among runners. Therefore, understanding the effects of fatigue in novice runners is an important issue.
Felix Möhler, Cagla Fadillioglu, Lucia Scheffler, Hermann Müller, Thorsten Stein   +4 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Hopf bifurcations in a three-species food chain system with multiple delays

Open Mathematics, 2017
This paper is concerned with a three-species Lotka-Volterra food chain system with multiple delays. By linearizing the system at the positive equilibrium and analyzing the associated characteristic equation, the stability of the positive equilibrium and ...
Xie Xiaoliang, Zhang Wen
doaj   +1 more source

Hopf bifurcation analysis of scalar implicit neutral delay differential equation

Electronic Journal of Qualitative Theory of Differential Equations, 2018
Hopf bifurcation analysis is conducted on a scalar implicit Neutral Delay Differential Equation (NDDE) by means of the extension of two analytical methods: 1) center manifold reduction combined with normal form theory; 2) method of multiple scales.
Li Zhang, Gábor Stépán
doaj   +1 more source

Analysis of SVEIL Model of Tuberculosis Disease Spread with Imperfect Vaccination

JTAM (Jurnal Teori dan Aplikasi Matematika), 2023
This study proposes a SVEIL model of tuberculosis disease spread with imperfect vaccination. Susceptible individuals can receive imperfect vaccination, but over the time the vaccine efficacy will decrease.
Handika Lintang Saputra, Isnani Darti, Agus Suryanto   +2 more
doaj   +1 more source

Center Manifold Reduction and Perturbation Method in a Delayed Model with a Mound-Shaped Cobb-Douglas Production Function

, 2013
Matsumoto and Szidarovszky (2011) examined a delayed continuous-time growth model with a special mound-shaped production function and showed a Hopf bifurcation that occurs when time delay passes through a critical value.
M. Ferrara, L. Guerrini, Giovanni Molica Bisci   +2 more
semanticscholar   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

The past and future dynamics of quintom dark energy models

European Physical Journal C: Particles and Fields, 2018
We study the phase space of the quintom cosmologies for a class of exponential potentials. We combine normal forms expansions and the center manifold theory in order to describe the dynamics near equilibrium sets.
Genly Leon, Andronikos Paliathanasis, Jorge Luis Morales-Martínez   +2 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source